Beginner Puzzle: Docking Design
Open for the next 12 days
BeginnerSummary
- Created
- February 19, 2026
- Expires
- Max points
- 100
We are giving you a helix positioned over a hydrophobic groove where binding occurs in nature. You can mutate any residue on the helix but none on the native binding region. Try to look for favorable hydrophobic interactions in this groove while maintaining the helix. For new players that have joined Foldit in the last 6 months.
