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Beginner Puzzle: Docking Design

Closed since about 2 months ago

Beginner Beginner Beginner Beginner Beginner Beginner

Summary

Created
February 19, 2026
Expires
Max points
100
Description

We are giving you a helix positioned over a hydrophobic groove where binding occurs in nature. You can mutate any residue on the helix but none on the native binding region. Try to look for favorable hydrophobic interactions in this groove while maintaining the helix. For new players that have joined Foldit in the last 6 months.

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