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366: Back Me Up 1

Closed since over 15 years ago

Intermediate

Summary

Created
September 27, 2010
Expires
Max points
100
Description

We designed a helix to contact our substrate, but the helix needs back up to stay in place. The goal of this puzzle is to design a loop and mutate residues to create a more stable configuration, making a more active catalyst (ie create a Helix-Loop-Helix). See the blogpost for more details: http://fold.it/portal/node/988587

Top groups

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  3. Avatar for OMNABEK 13. OMNABEK 4 pts. 14,087
  4. Avatar for Deleted group 14. Deleted group pts. 14,082
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  6. Avatar for Penny-Arcade 16. Penny-Arcade 1 pt. 14,070
  7. Avatar for L'Alliance Francophone 17. L'Alliance Francophone 1 pt. 14,064
  8. Avatar for Mmm Helix Fries. 18. Mmm Helix Fries. 1 pt. 14,059
  9. Avatar for Crunching Family 19. Crunching Family 1 pt. 14,054
  10. Avatar for xkcd 20. xkcd 1 pt. 14,037
  1. Avatar for mimi 21. mimi Lv 1 71 pts. 14,175
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  3. Avatar for Bletchley Park 23. Bletchley Park Lv 1 68 pts. 14,172
  4. Avatar for G d S 24. G d S Lv 1 67 pts. 14,171
  5. Avatar for Coskun 25. Coskun Lv 1 66 pts. 14,162
  6. Avatar for GaryForbis 26. GaryForbis Lv 1 64 pts. 14,157
  7. Avatar for SKSbell 27. SKSbell Lv 1 63 pts. 14,152
  8. Avatar for daijumao 28. daijumao Lv 1 62 pts. 14,149
  9. Avatar for Madde 29. Madde Lv 1 61 pts. 14,146
  10. Avatar for Lindax 30. Lindax Lv 1 60 pts. 14,146

Comments

beta_helix Staff Lv 1

We do not want you to change Alanine 54 or Glycine 55, however you are free to move the backbone there in order to make the helix move into a better position.

You cannot delete any residues, but you may add 0-5 residues anywhere between residues 44-54.