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366: Back Me Up 1

Closed since over 15 years ago

Intermediate Intermediate

Summary

Created
September 27, 2010
Expires
Max points
100
Description

We designed a helix to contact our substrate, but the helix needs back up to stay in place. The goal of this puzzle is to design a loop and mutate residues to create a more stable configuration, making a more active catalyst (ie create a Helix-Loop-Helix). See the blogpost for more details: http://fold.it/portal/node/988587

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  1. Avatar for photoelectric 281. photoelectric Lv 1 1 pt. 13,977
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  7. Avatar for amino acid 287. amino acid Lv 1 1 pt. 13,977
  8. Avatar for maxwell_thethird 288. maxwell_thethird Lv 1 1 pt. 13,977
  9. Avatar for prot-bustr 289. prot-bustr Lv 1 1 pt. 13,977
  10. Avatar for Ryanfav 290. Ryanfav Lv 1 1 pt. 13,977

Comments

beta_helix Staff Lv 1

We do not want you to change Alanine 54 or Glycine 55, however you are free to move the backbone there in order to make the helix move into a better position.

You cannot delete any residues, but you may add 0-5 residues anywhere between residues 44-54.