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366: Back Me Up 1

Closed since over 15 years ago

Intermediate

Summary

Created
September 27, 2010
Expires
Max points
100
Description

We designed a helix to contact our substrate, but the helix needs back up to stay in place. The goal of this puzzle is to design a loop and mutate residues to create a more stable configuration, making a more active catalyst (ie create a Helix-Loop-Helix). See the blogpost for more details: http://fold.it/portal/node/988587

Top groups

  1. Avatar for Contenders
    1. Contenders
    100 pts. 14,280
  2. Avatar for Void Crushers 2. Void Crushers 81 pts. 14,276
  3. Avatar for Russian team 3. Russian team 65 pts. 14,253
  4. Avatar for Richard Dawkins Foundation 4. Richard Dawkins Foundation 52 pts. 14,232
  5. Avatar for Anthropic Dreams 5. Anthropic Dreams 41 pts. 14,225
  6. Avatar for Deleted group 6. Deleted group pts. 14,199
  7. Avatar for Natural Abilities 7. Natural Abilities 24 pts. 14,177
  8. Avatar for SETI.Germany 8. SETI.Germany 18 pts. 14,145
  9. Avatar for Deleted group 9. Deleted group pts. 14,140
  10. Avatar for Mojo Risin' 10. Mojo Risin' 10 pts. 14,110
  1. Avatar for auntdeen 111. auntdeen Lv 1 10 pts. 14,074
  2. Avatar for jhullaert 112. jhullaert Lv 1 10 pts. 14,074
  3. Avatar for Datstandin 113. Datstandin Lv 1 9 pts. 14,073
  4. Avatar for Deleted player 114. Deleted player pts. 14,072
  5. Avatar for schm0o 115. schm0o Lv 1 9 pts. 14,072
  6. Avatar for heather-1 116. heather-1 Lv 1 9 pts. 14,072
  7. Avatar for synthetiq 117. synthetiq Lv 1 8 pts. 14,071
  8. Avatar for glaciall 118. glaciall Lv 1 8 pts. 14,071
  9. Avatar for wozzarelli 119. wozzarelli Lv 1 8 pts. 14,071
  10. Avatar for fireang3l 120. fireang3l Lv 1 8 pts. 14,070

Comments

beta_helix Staff Lv 1

We do not want you to change Alanine 54 or Glycine 55, however you are free to move the backbone there in order to make the helix move into a better position.

You cannot delete any residues, but you may add 0-5 residues anywhere between residues 44-54.