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366: Back Me Up 1

Closed since over 15 years ago

Intermediate

Summary

Created
September 27, 2010
Expires
Max points
100
Description

We designed a helix to contact our substrate, but the helix needs back up to stay in place. The goal of this puzzle is to design a loop and mutate residues to create a more stable configuration, making a more active catalyst (ie create a Helix-Loop-Helix). See the blogpost for more details: http://fold.it/portal/node/988587

Top groups

  1. Avatar for Contenders
    1. Contenders
    100 pts. 14,280
  2. Avatar for Void Crushers 2. Void Crushers 81 pts. 14,276
  3. Avatar for Russian team 3. Russian team 65 pts. 14,253
  4. Avatar for Richard Dawkins Foundation 4. Richard Dawkins Foundation 52 pts. 14,232
  5. Avatar for Anthropic Dreams 5. Anthropic Dreams 41 pts. 14,225
  6. Avatar for Deleted group 6. Deleted group pts. 14,199
  7. Avatar for Natural Abilities 7. Natural Abilities 24 pts. 14,177
  8. Avatar for SETI.Germany 8. SETI.Germany 18 pts. 14,145
  9. Avatar for Deleted group 9. Deleted group pts. 14,140
  10. Avatar for Mojo Risin' 10. Mojo Risin' 10 pts. 14,110
  1. Avatar for beta_helix 281. beta_helix Lv 1 1 pt. 13,977
  2. Avatar for Lord_c_nu 282. Lord_c_nu Lv 1 1 pt. 13,977
  3. Avatar for photoelectric 283. photoelectric Lv 1 1 pt. 13,977
  4. Avatar for triple_helix 284. triple_helix Lv 1 1 pt. 13,977
  5. Avatar for shaoo 285. shaoo Lv 1 1 pt. 13,977
  6. Avatar for sbuandrew 286. sbuandrew Lv 1 1 pt. 13,977
  7. Avatar for mtalajoor 287. mtalajoor Lv 1 1 pt. 13,977
  8. Avatar for derastov 288. derastov Lv 1 1 pt. 13,977
  9. Avatar for amino acid 289. amino acid Lv 1 1 pt. 13,977
  10. Avatar for maxwell_thethird 290. maxwell_thethird Lv 1 1 pt. 13,977

Comments

beta_helix Staff Lv 1

We do not want you to change Alanine 54 or Glycine 55, however you are free to move the backbone there in order to make the helix move into a better position.

You cannot delete any residues, but you may add 0-5 residues anywhere between residues 44-54.