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404: De-novo Freestyle 4

Closed since about 15 years ago

Advanced Overall Prediction

Summary

Created
March 09, 2011
Expires
Max points
100
Description

This currently unsolved protein does not have any templates that we can use, so we are giving it to you as an extended chain. Use all your skills to fold it up as best as you can. The secondary structure predictions are posted in the puzzle comments, but we have included them in the starting structure as well.

Top groups

  1. Avatar for Slovak National Team 11. Slovak National Team 8 pts. 9,947
  2. Avatar for Deleted group 12. Deleted group pts. 9,857
  3. Avatar for Deleted group 13. Deleted group pts. 9,831
  4. Avatar for L'Alliance Francophone 14. L'Alliance Francophone 3 pts. 9,828
  5. Avatar for Penny-Arcade 15. Penny-Arcade 2 pts. 9,679
  6. Avatar for Eὕρηκα! Heureka! 16. Eὕρηκα! Heureka! 2 pts. 9,612
  7. Avatar for TT-group 17. TT-group 1 pt. 9,609
  8. Avatar for Team Commonwealth 18. Team Commonwealth 1 pt. 9,522
  9. Avatar for Deleted group 19. Deleted group pts. 9,439
  10. Avatar for xkcd 20. xkcd 1 pt. 9,218
  1. Avatar for Seneca 161. Seneca Lv 1 1 pt. 8,608
  2. Avatar for kendrickt7 162. kendrickt7 Lv 1 1 pt. 8,594
  3. Avatar for Maxus7 163. Maxus7 Lv 1 1 pt. 8,585
  4. Avatar for azvolpe 164. azvolpe Lv 1 1 pt. 8,556
  5. Avatar for casaba 165. casaba Lv 1 1 pt. 8,548
  6. Avatar for oaks 166. oaks Lv 1 1 pt. 8,521
  7. Avatar for Lumir 167. Lumir Lv 1 1 pt. 8,520
  8. Avatar for Tres 168. Tres Lv 1 1 pt. 8,515
  9. Avatar for ceventer 169. ceventer Lv 1 1 pt. 8,514
  10. Avatar for cysteine.chapel 170. cysteine.chapel Lv 1 1 pt. 8,507

Comments

beta_helix Staff Lv 1

As requested in the feedback, http://fold.it/portal/node/989298, these secondary structure predictions have been pre-loaded into this freestyle puzzle.

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the amino acid Isoleucine at residue 29 is highly predicted to be part of a helix. However, the Leucine at residue 97 is predicted to have an equal probability of being anything.