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404: De-novo Freestyle 4

Closed since about 15 years ago

Advanced Overall Prediction

Summary

Created
March 09, 2011
Expires
Max points
100
Description

This currently unsolved protein does not have any templates that we can use, so we are giving it to you as an extended chain. Use all your skills to fold it up as best as you can. The secondary structure predictions are posted in the puzzle comments, but we have included them in the starting structure as well.

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Comments

beta_helix Staff Lv 1

As requested in the feedback, http://fold.it/portal/node/989298, these secondary structure predictions have been pre-loaded into this freestyle puzzle.

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the amino acid Isoleucine at residue 29 is highly predicted to be part of a helix. However, the Leucine at residue 97 is predicted to have an equal probability of being anything.