Placeholder image of a protein
Icon representing a puzzle

404: De-novo Freestyle 4

Closed since about 15 years ago

Advanced Overall Prediction

Summary

Created
March 09, 2011
Expires
Max points
100
Description

This currently unsolved protein does not have any templates that we can use, so we are giving it to you as an extended chain. Use all your skills to fold it up as best as you can. The secondary structure predictions are posted in the puzzle comments, but we have included them in the starting structure as well.

Top groups

  1. Avatar for Crunching Family 21. Crunching Family 1 pt. 8,900
  2. Avatar for Russian team 22. Russian team 1 pt. 8,612
  3. Avatar for Czech National Team 23. Czech National Team 1 pt. 8,520
  4. Avatar for Extraterrestrials 24. Extraterrestrials 1 pt. 8,207
  5. Avatar for Richard Dawkins Foundation 25. Richard Dawkins Foundation 1 pt. 7,736
  6. Avatar for DSN @ Home 26. DSN @ Home 1 pt. 7,342
  1. Avatar for ntdna 241. ntdna Lv 1 1 pt. 7,341
  2. Avatar for sg1maniac 242. sg1maniac Lv 1 1 pt. 7,341
  3. Avatar for Damaged4Good 243. Damaged4Good Lv 1 1 pt. 7,340
  4. Avatar for DAK719 244. DAK719 Lv 1 1 pt. 7,257
  5. Avatar for prnelson 245. prnelson Lv 1 1 pt. 7,251
  6. Avatar for Renkal 246. Renkal Lv 1 1 pt. 7,228
  7. Avatar for ixiaohoui 247. ixiaohoui Lv 1 1 pt. 7,195
  8. Avatar for din0_s4ur0 248. din0_s4ur0 Lv 1 1 pt. 7,044
  9. Avatar for Alderon 249. Alderon Lv 1 1 pt. 6,873
  10. Avatar for arteYciencia 250. arteYciencia Lv 1 1 pt. 6,404

Comments

beta_helix Staff Lv 1

As requested in the feedback, http://fold.it/portal/node/989298, these secondary structure predictions have been pre-loaded into this freestyle puzzle.

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the amino acid Isoleucine at residue 29 is highly predicted to be part of a helix. However, the Leucine at residue 97 is predicted to have an equal probability of being anything.