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406: Freestyle Nitric Oxide Puzzle

Closed since about 15 years ago

Advanced Overall Prediction

Summary

Created
March 22, 2011
Expires
Max points
100
Description

***SEQUENCE LOGO NOW POSTED IN PUZZLE COMMENTS*** There will be more puzzles about this currently unsolved protein, but we wanted to start you off with it as an extended chain. Use all your skills to fold it up as best as you can. We will post a blog with details about this protein soon!

Top groups

  1. Avatar for Eὕρηκα! Heureka! 21. Eὕρηκα! Heureka! 1 pt. 9,996
  2. Avatar for Crunching Family 22. Crunching Family 1 pt. 9,585
  3. Avatar for Extraterrestrials 23. Extraterrestrials 1 pt. 8,473
  4. Avatar for Australia 24. Australia 1 pt. 7,277
  5. Avatar for DSN @ Home 25. DSN @ Home 1 pt. 7,128
  6. Avatar for xkcd 26. xkcd 1 pt. 3,554
  1. Avatar for Arne Heessels 131. Arne Heessels Lv 1 4 pts. 9,730
  2. Avatar for mirjamvandelft 132. mirjamvandelft Lv 1 4 pts. 9,722
  3. Avatar for maxwell_thethird 133. maxwell_thethird Lv 1 4 pts. 9,721
  4. Avatar for sbea3 134. sbea3 Lv 1 4 pts. 9,683
  5. Avatar for weurhartdezirez 135. weurhartdezirez Lv 1 4 pts. 9,665
  6. Avatar for hkilik 136. hkilik Lv 1 4 pts. 9,656
  7. Avatar for Deleted player 137. Deleted player 4 pts. 9,623
  8. Avatar for fractalman 138. fractalman Lv 1 4 pts. 9,617
  9. Avatar for Daurer 139. Daurer Lv 1 3 pts. 9,610
  10. Avatar for EALs DAD 140. EALs DAD Lv 1 3 pts. 9,597

Comments

beta_helix Staff Lv 1

The SAM T08 server seems to be down, so we used some basic secondary structure predictions (which are the ones shown in the puzzle)

We'll post a sequence logo when the SAM server comes back up!

beta_helix Staff Lv 1

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the amino acid Isoleucine at residue 25 is highly predicted to be part of a helix. However, the Leucine at residue 133 is predicted to be part of a beta sheet.