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406: Freestyle Nitric Oxide Puzzle

Closed since about 15 years ago

Advanced Overall Prediction

Summary

Created
March 22, 2011
Expires
Max points
100
Description

***SEQUENCE LOGO NOW POSTED IN PUZZLE COMMENTS*** There will be more puzzles about this currently unsolved protein, but we wanted to start you off with it as an extended chain. Use all your skills to fold it up as best as you can. We will post a blog with details about this protein soon!

Top groups

  1. Avatar for Eὕρηκα! Heureka! 21. Eὕρηκα! Heureka! 1 pt. 9,996
  2. Avatar for Crunching Family 22. Crunching Family 1 pt. 9,585
  3. Avatar for Extraterrestrials 23. Extraterrestrials 1 pt. 8,473
  4. Avatar for Australia 24. Australia 1 pt. 7,277
  5. Avatar for DSN @ Home 25. DSN @ Home 1 pt. 7,128
  6. Avatar for xkcd 26. xkcd 1 pt. 3,554
  1. Avatar for Cosi 201. Cosi Lv 1 1 pt. 7,270
  2. Avatar for cysteine.chapel 202. cysteine.chapel Lv 1 1 pt. 7,256
  3. Avatar for Hell_Kitty 203. Hell_Kitty Lv 1 1 pt. 7,254
  4. Avatar for Ethan_Ol 204. Ethan_Ol Lv 1 1 pt. 7,252
  5. Avatar for megftw 205. megftw Lv 1 1 pt. 7,245
  6. Avatar for iamleslie 206. iamleslie Lv 1 1 pt. 7,234
  7. Avatar for kbob 207. kbob Lv 1 1 pt. 7,225
  8. Avatar for RAntonello1 208. RAntonello1 Lv 1 1 pt. 7,217
  9. Avatar for Arromus 209. Arromus Lv 1 1 pt. 7,209
  10. Avatar for mya 210. mya Lv 1 1 pt. 7,209

Comments

beta_helix Staff Lv 1

The SAM T08 server seems to be down, so we used some basic secondary structure predictions (which are the ones shown in the puzzle)

We'll post a sequence logo when the SAM server comes back up!

beta_helix Staff Lv 1

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the amino acid Isoleucine at residue 25 is highly predicted to be part of a helix. However, the Leucine at residue 133 is predicted to be part of a beta sheet.