Placeholder image of a protein
Icon representing a puzzle

406: Freestyle Nitric Oxide Puzzle

Closed since about 15 years ago

Advanced Overall Prediction

Summary

Created
March 22, 2011
Expires
Max points
100
Description

***SEQUENCE LOGO NOW POSTED IN PUZZLE COMMENTS*** There will be more puzzles about this currently unsolved protein, but we wanted to start you off with it as an extended chain. Use all your skills to fold it up as best as you can. We will post a blog with details about this protein soon!

Top groups

  1. Avatar for Eὕρηκα! Heureka! 21. Eὕρηκα! Heureka! 1 pt. 9,996
  2. Avatar for Crunching Family 22. Crunching Family 1 pt. 9,585
  3. Avatar for Extraterrestrials 23. Extraterrestrials 1 pt. 8,473
  4. Avatar for Australia 24. Australia 1 pt. 7,277
  5. Avatar for DSN @ Home 25. DSN @ Home 1 pt. 7,128
  6. Avatar for xkcd 26. xkcd 1 pt. 3,554
  1. Avatar for martinzblavy 31. martinzblavy Lv 1 56 pts. 11,393
  2. Avatar for Ch Garnier 32. Ch Garnier Lv 1 55 pts. 11,370
  3. Avatar for pauldunn 33. pauldunn Lv 1 54 pts. 11,359
  4. Avatar for monteecristo 34. monteecristo Lv 1 53 pts. 11,359
  5. Avatar for strong_base 35. strong_base Lv 1 52 pts. 11,342
  6. Avatar for fishercat 36. fishercat Lv 1 51 pts. 11,341
  7. Avatar for gdnskye 37. gdnskye Lv 1 50 pts. 11,304
  8. Avatar for shettler 38. shettler Lv 1 49 pts. 11,302
  9. Avatar for justjustin 39. justjustin Lv 1 48 pts. 11,265
  10. Avatar for HillObserver 40. HillObserver Lv 1 47 pts. 11,259

Comments

beta_helix Staff Lv 1

The SAM T08 server seems to be down, so we used some basic secondary structure predictions (which are the ones shown in the puzzle)

We'll post a sequence logo when the SAM server comes back up!

beta_helix Staff Lv 1

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the amino acid Isoleucine at residue 25 is highly predicted to be part of a helix. However, the Leucine at residue 133 is predicted to be part of a beta sheet.