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410: De-novo Freestyle 5

Closed since almost 15 years ago

Advanced Overall Prediction

Summary

Created
April 05, 2011
Expires
Max points
100
Description

We are giving it to you this currently unsolved protein as an extended chain. Use all your skills to fold it up as best as you can. The secondary structure predictions are posted in the puzzle comments, but we have included them in the starting structure as well. Since this protein chain is quite long, we are giving you 2 extra days to work on it.

Top groups

  1. Avatar for Czech National Team 21. Czech National Team 1 pt. 8,071
  2. Avatar for Buffalo Lab 22. Buffalo Lab 1 pt. 8,066
  3. Avatar for Street Smarts 23. Street Smarts 1 pt. 7,980
  4. Avatar for Extraterrestrials 24. Extraterrestrials 1 pt. 7,027
  5. Avatar for DSN @ Home 25. DSN @ Home 1 pt. 7,026
  6. Avatar for BOINC@Poland 26. BOINC@Poland 1 pt. 6,976
  7. Avatar for CMU-PITT Comp Bio 27. CMU-PITT Comp Bio 1 pt. 4,572
  8. Avatar for Team China 28. Team China 1 pt. 1,541
  1. Avatar for scottyler89
    1. scottyler89 Lv 1
    100 pts. 12,729
  2. Avatar for strong_base 2. strong_base Lv 1 99 pts. 12,706
  3. Avatar for groovermctuber 3. groovermctuber Lv 1 97 pts. 12,631
  4. Avatar for Grom 4. Grom Lv 1 96 pts. 12,576
  5. Avatar for spmm 5. spmm Lv 1 94 pts. 12,545
  6. Avatar for deus911 6. deus911 Lv 1 92 pts. 12,528
  7. Avatar for monteecristo 7. monteecristo Lv 1 91 pts. 12,501
  8. Avatar for Mark- 8. Mark- Lv 1 89 pts. 12,493
  9. Avatar for pauldunn 9. pauldunn Lv 1 88 pts. 12,490
  10. Avatar for philcalhoun 10. philcalhoun Lv 1 86 pts. 12,479

Comments

beta_helix Staff Lv 1

As requested in the feedback, http://fold.it/portal/node/989298 these secondary structure predictions have been pre-loaded into this freestyle puzzle.

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the amino acid Isoleucine at residue 23 is highly predicted to be part of a helix. However, the Threonine at residue 102 is predicted to have an equal probability of being anything.

CupcakeLulu Lv 1

Kinda hard to download I wish it were already loaded onto the site but it's a fun and educational game. I'd rate it four point five stars out of five stars.