Placeholder image of a protein
Icon representing a puzzle

413: De-novo Freestyle 6

Closed since almost 15 years ago

Advanced Overall Prediction

Summary

Created
April 23, 2011
Expires
Max points
100
Description

We are giving it to you this currently unsolved protein as an extended chain. Use all your skills to fold it up as best as you can. The secondary structure predictions are posted in the puzzle comments, but we have included them in the starting structure as well. Since this protein chain is quite long, we are giving you 3 extra days to work on it.

Top groups

  1. Avatar for Deleted group 11. Deleted group pts. 12,029
  2. Avatar for L'Alliance Francophone 12. L'Alliance Francophone 12 pts. 12,024
  3. Avatar for Deleted group 13. Deleted group pts. 11,814
  4. Avatar for Purdue BoilerFolders 14. Purdue BoilerFolders 7 pts. 11,378
  5. Avatar for Argentina 15. Argentina 5 pts. 11,369
  6. Avatar for Speedfolders 16. Speedfolders 4 pts. 11,212
  7. Avatar for Eὕρηκα! Heureka! 17. Eὕρηκα! Heureka! 3 pts. 11,065
  8. Avatar for University of Washington 18. University of Washington 2 pts. 10,277
  9. Avatar for Mojo Risin' 19. Mojo Risin' 2 pts. 10,030
  10. Avatar for Crunching Family 20. Crunching Family 1 pt. 9,749
  1. Avatar for janmaartenfernig 191. janmaartenfernig Lv 1 2 pts. 8,338
  2. Avatar for Norbinator 192. Norbinator Lv 1 2 pts. 8,311
  3. Avatar for beta68 193. beta68 Lv 1 2 pts. 8,243
  4. Avatar for martinf 194. martinf Lv 1 2 pts. 8,240
  5. Avatar for Phaiix 195. Phaiix Lv 1 2 pts. 8,228
  6. Avatar for aspadistra 196. aspadistra Lv 1 2 pts. 8,168
  7. Avatar for Fowardint 197. Fowardint Lv 1 2 pts. 8,166
  8. Avatar for Tavarielle 198. Tavarielle Lv 1 2 pts. 8,130
  9. Avatar for zigditel 199. zigditel Lv 1 2 pts. 8,092
  10. Avatar for madpenguin 200. madpenguin Lv 1 2 pts. 8,023

Comments

beta_helix Staff Lv 1

As requested in the feedback, http://fold.it/portal/node/989298 these secondary structure predictions have been pre-loaded into this freestyle puzzle.

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the amino acid Leucine at residue 171 is highly predicted to be part of a helix. However, the Leucine at residue 154 is equally predicted to be a sheet or loop.