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413: De-novo Freestyle 6

Closed since almost 15 years ago

Advanced Advanced Overall Overall Prediction Prediction

Summary

Created
April 23, 2011
Expires
Max points
100
Description

We are giving it to you this currently unsolved protein as an extended chain. Use all your skills to fold it up as best as you can. The secondary structure predictions are posted in the puzzle comments, but we have included them in the starting structure as well. Since this protein chain is quite long, we are giving you 3 extra days to work on it.

Top groups

  1. Avatar for Richard Dawkins Foundation 21. Richard Dawkins Foundation 1 pt. 9,260
  2. Avatar for Pauling's Pitbulls 22. Pauling's Pitbulls 1 pt. 9,131
  3. Avatar for Deleted group 23. Deleted group pts. 8,882
  4. Avatar for DSN @ Home 24. DSN @ Home 1 pt. 8,168
  5. Avatar for Extraterrestrials 25. Extraterrestrials 1 pt. 8,023
  6. Avatar for Deleted group 26. Deleted group pts. 7,720
  7. Avatar for Czech National Team 27. Czech National Team 1 pt. 7,176
  8. Avatar for Nerdfighters 28. Nerdfighters 1 pt. 7,157
  9. Avatar for Penny-Arcade 29. Penny-Arcade 1 pt. 7,145
  10. Avatar for Team China 30. Team China 1 pt. 6,370
  1. Avatar for Goatchrist666 261. Goatchrist666 Lv 1 1 pt. 7,144
  2. Avatar for Deleted player 262. Deleted player pts. 7,142
  3. Avatar for Merovingiens 263. Merovingiens Lv 1 1 pt. 7,142
  4. Avatar for NewLive42 264. NewLive42 Lv 1 1 pt. 7,142
  5. Avatar for Deleted player 265. Deleted player pts. 7,142
  6. Avatar for robestone 266. robestone Lv 1 1 pt. 7,142
  7. Avatar for jcangst 267. jcangst Lv 1 1 pt. 7,142
  8. Avatar for Jocky 268. Jocky Lv 1 1 pt. 7,141
  9. Avatar for Natsume 269. Natsume Lv 1 1 pt. 7,139
  10. Avatar for edgar.stein 270. edgar.stein Lv 1 1 pt. 7,139

Comments

beta_helix Staff Lv 1

As requested in the feedback, http://fold.it/portal/node/989298 these secondary structure predictions have been pre-loaded into this freestyle puzzle.

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the amino acid Leucine at residue 171 is highly predicted to be part of a helix. However, the Leucine at residue 154 is equally predicted to be a sheet or loop.