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413: De-novo Freestyle 6

Closed since almost 15 years ago

Advanced Overall Prediction

Summary

Created
April 23, 2011
Expires
Max points
100
Description

We are giving it to you this currently unsolved protein as an extended chain. Use all your skills to fold it up as best as you can. The secondary structure predictions are posted in the puzzle comments, but we have included them in the starting structure as well. Since this protein chain is quite long, we are giving you 3 extra days to work on it.

Top groups

  1. Avatar for Richard Dawkins Foundation 21. Richard Dawkins Foundation 1 pt. 9,260
  2. Avatar for Pauling's Pitbulls 22. Pauling's Pitbulls 1 pt. 9,131
  3. Avatar for Deleted group 23. Deleted group pts. 8,882
  4. Avatar for DSN @ Home 24. DSN @ Home 1 pt. 8,168
  5. Avatar for Extraterrestrials 25. Extraterrestrials 1 pt. 8,023
  6. Avatar for Deleted group 26. Deleted group pts. 7,720
  7. Avatar for Czech National Team 27. Czech National Team 1 pt. 7,176
  8. Avatar for Nerdfighters 28. Nerdfighters 1 pt. 7,157
  9. Avatar for Penny-Arcade 29. Penny-Arcade 1 pt. 7,145
  10. Avatar for Team China 30. Team China 1 pt. 6,370
  1. Avatar for Jim Fraser 31. Jim Fraser Lv 1 63 pts. 12,374
  2. Avatar for caglar 32. caglar Lv 1 62 pts. 12,368
  3. Avatar for Grom 33. Grom Lv 1 61 pts. 12,348
  4. Avatar for Dolichwier 34. Dolichwier Lv 1 60 pts. 12,304
  5. Avatar for delawarekid 35. delawarekid Lv 1 59 pts. 12,299
  6. Avatar for Susanne 36. Susanne Lv 1 58 pts. 12,258
  7. Avatar for cbwest 37. cbwest Lv 1 57 pts. 12,253
  8. Avatar for rsosborne 38. rsosborne Lv 1 56 pts. 12,251
  9. Avatar for johnmitch 39. johnmitch Lv 1 55 pts. 12,247
  10. Avatar for gcm24 40. gcm24 Lv 1 54 pts. 12,246

Comments

beta_helix Staff Lv 1

As requested in the feedback, http://fold.it/portal/node/989298 these secondary structure predictions have been pre-loaded into this freestyle puzzle.

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the amino acid Leucine at residue 171 is highly predicted to be part of a helix. However, the Leucine at residue 154 is equally predicted to be a sheet or loop.