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413: De-novo Freestyle 6

Closed since almost 15 years ago

Advanced Overall Prediction

Summary

Created
April 23, 2011
Expires
Max points
100
Description

We are giving it to you this currently unsolved protein as an extended chain. Use all your skills to fold it up as best as you can. The secondary structure predictions are posted in the puzzle comments, but we have included them in the starting structure as well. Since this protein chain is quite long, we are giving you 3 extra days to work on it.

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Comments

beta_helix Staff Lv 1

As requested in the feedback, http://fold.it/portal/node/989298 these secondary structure predictions have been pre-loaded into this freestyle puzzle.

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the amino acid Leucine at residue 171 is highly predicted to be part of a helix. However, the Leucine at residue 154 is equally predicted to be a sheet or loop.