Placeholder image of a protein
Icon representing a puzzle

432: De-novo Freestyle 8

Closed since over 14 years ago

Advanced Overall Prediction

Summary

Created
June 19, 2011
Expires
Max points
100
Description

We are giving you this currently unsolved protein as an extended chain. Use all your skills to fold it up as best as you can. The secondary structure predictions are posted in the puzzle comments, but we have included them in the starting structure as well.

Top groups

  1. Avatar for Eὕρηκα! Heureka! 21. Eὕρηκα! Heureka! 1 pt. 8,705
  2. Avatar for Penny-Arcade 22. Penny-Arcade 1 pt. 8,701
  3. Avatar for Deleted group 23. Deleted group pts. 8,636
  4. Avatar for Nerdfighters 24. Nerdfighters 1 pt. 8,620
  5. Avatar for Crunching Family 25. Crunching Family 1 pt. 8,486
  6. Avatar for Glufianz 26. Glufianz 1 pt. 8,167
  7. Avatar for Czech National Team 27. Czech National Team 1 pt. 8,084
  8. Avatar for Richard Dawkins Foundation 28. Richard Dawkins Foundation 1 pt. 7,482
  9. Avatar for Friday Lab 29. Friday Lab 1 pt. 7,467
  10. Avatar for DSN @ Home 30. DSN @ Home 1 pt. 7,467
  1. Avatar for bluefrog888 241. bluefrog888 Lv 1 1 pt. 7,482
  2. Avatar for Anubis278 242. Anubis278 Lv 1 1 pt. 7,481
  3. Avatar for HanQG 243. HanQG Lv 1 1 pt. 7,477
  4. Avatar for AeroQC 244. AeroQC Lv 1 1 pt. 7,471
  5. Avatar for zigzagwanderer 245. zigzagwanderer Lv 1 1 pt. 7,467
  6. Avatar for oxyi 246. oxyi Lv 1 1 pt. 7,467
  7. Avatar for andythom 247. andythom Lv 1 1 pt. 7,467
  8. Avatar for plh 248. plh Lv 1 1 pt. 7,467
  9. Avatar for aspadistra 249. aspadistra Lv 1 1 pt. 7,467
  10. Avatar for bobertsokrkid 250. bobertsokrkid Lv 1 1 pt. 7,466

Comments

beta_helix Staff Lv 1

As requested in the feedback, http://fold.it/portal/node/989298 these secondary structure predictions have been pre-loaded into this freestyle puzzle.

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the amino acid Leucine at residue 83 is highly predicted to be part of a sheet. However, the Phenylalanine at residue 29 is equally predicted to be in a sheet or loop (so it's probably not in a helix!).