Placeholder image of a protein
Icon representing a puzzle

432: De-novo Freestyle 8

Closed since over 14 years ago

Advanced Overall Prediction

Summary

Created
June 19, 2011
Expires
Max points
100
Description

We are giving you this currently unsolved protein as an extended chain. Use all your skills to fold it up as best as you can. The secondary structure predictions are posted in the puzzle comments, but we have included them in the starting structure as well.

Top groups

  1. Avatar for Anthropic Dreams
    1. Anthropic Dreams
    100 pts. 10,048
  2. Avatar for foldeRNA 2. foldeRNA 85 pts. 10,008
  3. Avatar for Contenders 3. Contenders 71 pts. 9,944
  4. Avatar for Void Crushers 4. Void Crushers 60 pts. 9,872
  5. Avatar for Go Science 5. Go Science 49 pts. 9,808
  6. Avatar for L'Alliance Francophone 6. L'Alliance Francophone 41 pts. 9,787
  7. Avatar for Russian team 7. Russian team 33 pts. 9,774
  8. Avatar for Deleted group 8. Deleted group pts. 9,478
  9. Avatar for SETI.Germany 9. SETI.Germany 22 pts. 9,440
  10. Avatar for Deleted group 10. Deleted group pts. 9,381
  1. Avatar for Deleted player 101. Deleted player pts. 9,122
  2. Avatar for Steve001 102. Steve001 Lv 1 10 pts. 9,114
  3. Avatar for Merf 103. Merf Lv 1 10 pts. 9,108
  4. Avatar for davidla 104. davidla Lv 1 10 pts. 9,099
  5. Avatar for jkang28 105. jkang28 Lv 1 9 pts. 9,099
  6. Avatar for justjustin 106. justjustin Lv 1 9 pts. 9,098
  7. Avatar for alphaCentauri 107. alphaCentauri Lv 1 9 pts. 9,094
  8. Avatar for Museka 108. Museka Lv 1 9 pts. 9,085
  9. Avatar for wenskye 109. wenskye Lv 1 8 pts. 9,065
  10. Avatar for anthunk 110. anthunk Lv 1 8 pts. 9,055

Comments

beta_helix Staff Lv 1

As requested in the feedback, http://fold.it/portal/node/989298 these secondary structure predictions have been pre-loaded into this freestyle puzzle.

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the amino acid Leucine at residue 83 is highly predicted to be part of a sheet. However, the Phenylalanine at residue 29 is equally predicted to be in a sheet or loop (so it's probably not in a helix!).