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443: Mini Arabidopsis Multi-Start Puzzle

Closed since over 14 years ago

Intermediate Overall Prediction

Summary


Created
July 27, 2011
Expires
Max points
100
Description

This small unsolved Arabidopsis protein only has 59 residues and negatively controls the biosynthesis of starch in plants and regulates leaf and seed composition. We are giving you 5 Zhang server models as starts for this puzzle. Each time you reset the puzzle one of them will randomly be chosen. They are also in the Alignment Tool so you can use partial threading and an extended chain. More info in the puzzle comments.

Top groups


  1. Avatar for DSN @ Home 21. DSN @ Home 1 pt. 8,167
  2. Avatar for The Archers 22. The Archers 1 pt. 8,145

  1. Avatar for heather-1 41. heather-1 Lv 1 31 pts. 9,089
  2. Avatar for wenskye 42. wenskye Lv 1 30 pts. 9,081
  3. Avatar for BitSpawn 43. BitSpawn Lv 1 29 pts. 9,080
  4. Avatar for jhullaert 44. jhullaert Lv 1 28 pts. 9,073
  5. Avatar for shettler 45. shettler Lv 1 28 pts. 9,070
  6. Avatar for Hanto_FZ140E_4G 46. Hanto_FZ140E_4G Lv 1 27 pts. 9,066
  7. Avatar for tyler0911 47. tyler0911 Lv 1 26 pts. 9,066
  8. Avatar for jbrussell93 48. jbrussell93 Lv 1 25 pts. 9,062
  9. Avatar for Flagg65a 49. Flagg65a Lv 1 24 pts. 9,061
  10. Avatar for aendgraend 50. aendgraend Lv 1 23 pts. 9,058

Comments


beta_helix Staff Lv 1

In the long term, it has potential applications in controlling the amount of oil, protein, and/or starch that is stored in seeds. The mechanism by which it regulates composition is not understood.

Solving this structure would not only help guide our experimentation to test its structure, but also help us in understanding its potential regulatory partners, and ultimately in understanding how carbon flux in plants is controlled.

More info about how this protein negatively controls the bio-synthesis of starch in plants and regulates leaf and seed composition:
http://onlinelibrary.wiley.com/doi/10.1111/j.1365-313X.2009.03793.x/full