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443: Mini Arabidopsis Multi-Start Puzzle

Closed since over 14 years ago

Intermediate Overall Prediction

Summary

Created
July 27, 2011
Expires
Max points
100
Description

This small unsolved Arabidopsis protein only has 59 residues and negatively controls the biosynthesis of starch in plants and regulates leaf and seed composition. We are giving you 5 Zhang server models as starts for this puzzle. Each time you reset the puzzle one of them will randomly be chosen. They are also in the Alignment Tool so you can use partial threading and an extended chain. More info in the puzzle comments.

Top groups

  1. Avatar for DSN @ Home 21. DSN @ Home 1 pt. 8,167
  2. Avatar for The Archers 22. The Archers 1 pt. 8,145
  1. Avatar for weitzen 61. weitzen Lv 1 16 pts. 9,030
  2. Avatar for NinjaGreg 62. NinjaGreg Lv 1 15 pts. 9,029
  3. Avatar for Deleted player 63. Deleted player pts. 9,028
  4. Avatar for B_2 64. B_2 Lv 1 14 pts. 9,027
  5. Avatar for LUKE1967 65. LUKE1967 Lv 1 13 pts. 9,024
  6. Avatar for caglar 66. caglar Lv 1 13 pts. 9,023
  7. Avatar for keypad5 67. keypad5 Lv 1 13 pts. 9,019
  8. Avatar for Deleted player 68. Deleted player pts. 9,017
  9. Avatar for Jim Fraser 69. Jim Fraser Lv 1 12 pts. 9,016
  10. Avatar for Parclytaxel 70. Parclytaxel Lv 1 11 pts. 9,012

Comments

beta_helix Staff Lv 1

In the long term, it has potential applications in controlling the amount of oil, protein, and/or starch that is stored in seeds. The mechanism by which it regulates composition is not understood.

Solving this structure would not only help guide our experimentation to test its structure, but also help us in understanding its potential regulatory partners, and ultimately in understanding how carbon flux in plants is controlled.

More info about how this protein negatively controls the bio-synthesis of starch in plants and regulates leaf and seed composition:
http://onlinelibrary.wiley.com/doi/10.1111/j.1365-313X.2009.03793.x/full