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443: Mini Arabidopsis Multi-Start Puzzle

Closed since over 14 years ago

Intermediate Overall Prediction

Summary

Created
July 27, 2011
Expires
Max points
100
Description

This small unsolved Arabidopsis protein only has 59 residues and negatively controls the biosynthesis of starch in plants and regulates leaf and seed composition. We are giving you 5 Zhang server models as starts for this puzzle. Each time you reset the puzzle one of them will randomly be chosen. They are also in the Alignment Tool so you can use partial threading and an extended chain. More info in the puzzle comments.

Top groups

  1. Avatar for DSN @ Home 21. DSN @ Home 1 pt. 8,167
  2. Avatar for The Archers 22. The Archers 1 pt. 8,145
  1. Avatar for Dolichwier 71. Dolichwier Lv 1 11 pts. 9,008
  2. Avatar for PRL 72. PRL Lv 1 10 pts. 9,003
  3. Avatar for sjoerdouwe 73. sjoerdouwe Lv 1 10 pts. 9,001
  4. Avatar for Tyggy Too 74. Tyggy Too Lv 1 10 pts. 9,000
  5. Avatar for yoyo washington 75. yoyo washington Lv 1 9 pts. 8,998
  6. Avatar for Susanne 76. Susanne Lv 1 9 pts. 8,993
  7. Avatar for Fat Tony 77. Fat Tony Lv 1 8 pts. 8,979
  8. Avatar for Tlaloc 78. Tlaloc Lv 1 8 pts. 8,978
  9. Avatar for Mr_Jolty 79. Mr_Jolty Lv 1 8 pts. 8,976
  10. Avatar for djag 80. djag Lv 1 7 pts. 8,976

Comments

beta_helix Staff Lv 1

In the long term, it has potential applications in controlling the amount of oil, protein, and/or starch that is stored in seeds. The mechanism by which it regulates composition is not understood.

Solving this structure would not only help guide our experimentation to test its structure, but also help us in understanding its potential regulatory partners, and ultimately in understanding how carbon flux in plants is controlled.

More info about how this protein negatively controls the bio-synthesis of starch in plants and regulates leaf and seed composition:
http://onlinelibrary.wiley.com/doi/10.1111/j.1365-313X.2009.03793.x/full