Placeholder image of a protein
Icon representing a puzzle

460: Quest to the SOLVED Monkey Virus Protein

Closed since over 14 years ago

Intermediate Overall Prediction

Summary

Created
September 23, 2011
Expires
Max points
100
Description

The crystal structure of monomeric M-PMV retroviral protease, which causes AIDS in rhesus monkeys, has finally been released. You may have read about this protein in the news recently... so we thought we should post it again as a Quest to the Native. Once again we are giving you the 10 NMR models to work on, they are also in the Alignment Tool. After threading, make sure to press G to Align the Guide. We're sure you can get even closer to the native this time, and in less than 10 days!

Top groups

  1. Avatar for Deleted group 11. Deleted group pts. 10,014
  2. Avatar for xkcd 12. xkcd 28 pts. 9,975
  3. Avatar for Purdue BoilerFolders 13. Purdue BoilerFolders 24 pts. 9,967
  4. Avatar for L'Alliance Francophone 14. L'Alliance Francophone 21 pts. 9,966
  5. Avatar for Deleted group 15. Deleted group pts. 9,919
  6. Avatar for Deleted group 16. Deleted group pts. 9,874
  7. Avatar for SETI.Germany 17. SETI.Germany 14 pts. 9,852
  8. Avatar for Richard Dawkins Foundation 18. Richard Dawkins Foundation 12 pts. 9,791
  9. Avatar for Mojo Risin' 19. Mojo Risin' 10 pts. 9,783
  10. Avatar for Deleted group 20. Deleted group pts. 9,766
  1. Avatar for atakauji 1131. atakauji Lv 1 1 pt. 3,533
  2. Avatar for moriandrizzt 1132. moriandrizzt Lv 1 1 pt. 3,389
  3. Avatar for guandaslug 1133. guandaslug Lv 1 1 pt. 3,389
  4. Avatar for estevancontreras 1134. estevancontreras Lv 1 1 pt. 3,376
  5. Avatar for zek 1135. zek Lv 1 1 pt. 3,158
  6. Avatar for ksy6749 1136. ksy6749 Lv 1 1 pt. 2,920
  7. Avatar for rmabiochem101 1137. rmabiochem101 Lv 1 1 pt. 2,884
  8. Avatar for bornflying79 1138. bornflying79 Lv 1 1 pt. 2,770
  9. Avatar for mikefolder2 1139. mikefolder2 Lv 1 1 pt. 2,720
  10. Avatar for spazzz29 1140. spazzz29 Lv 1 1 pt. 2,636

Comments

beta_helix Staff Lv 1

This is the Quest to the Native version of Puzzle 390:
http://fold.it/portal/node/989012

Now that the protein has been solved (thanks to all of you), the PDB has posted the solution:
http://pdb.rcsb.org/pdb/explore.do?structureId=3SQF

For hints on how to use Partial Threading with the Alignment Tool, check out: http://fold.it/portal/node/989012#comment-9780

And if you weren't playing Foldit last December and want to see if you would have been able to get close to the native, you can always turn off the guide by press Shift-S.