Placeholder image of a protein
Icon representing a puzzle

460: Quest to the SOLVED Monkey Virus Protein

Closed since over 14 years ago

Intermediate Overall Prediction

Summary

Created
September 23, 2011
Expires
Max points
100
Description

The crystal structure of monomeric M-PMV retroviral protease, which causes AIDS in rhesus monkeys, has finally been released. You may have read about this protein in the news recently... so we thought we should post it again as a Quest to the Native. Once again we are giving you the 10 NMR models to work on, they are also in the Alignment Tool. After threading, make sure to press G to Align the Guide. We're sure you can get even closer to the native this time, and in less than 10 days!

Top groups

  1. Avatar for Deleted group 11. Deleted group pts. 10,014
  2. Avatar for xkcd 12. xkcd 28 pts. 9,975
  3. Avatar for Purdue BoilerFolders 13. Purdue BoilerFolders 24 pts. 9,967
  4. Avatar for L'Alliance Francophone 14. L'Alliance Francophone 21 pts. 9,966
  5. Avatar for Deleted group 15. Deleted group pts. 9,919
  6. Avatar for Deleted group 16. Deleted group pts. 9,874
  7. Avatar for SETI.Germany 17. SETI.Germany 14 pts. 9,852
  8. Avatar for Richard Dawkins Foundation 18. Richard Dawkins Foundation 12 pts. 9,791
  9. Avatar for Mojo Risin' 19. Mojo Risin' 10 pts. 9,783
  10. Avatar for Deleted group 20. Deleted group pts. 9,766
  1. Avatar for shettler 111. shettler Lv 1 65 pts. 9,748
  2. Avatar for ncm25_OLD 112. ncm25_OLD Lv 1 65 pts. 9,743
  3. Avatar for Museka 113. Museka Lv 1 65 pts. 9,742
  4. Avatar for doug.ehlert 114. doug.ehlert Lv 1 65 pts. 9,741
  5. Avatar for anne romaine 115. anne romaine Lv 1 64 pts. 9,730
  6. Avatar for barbaranne 116. barbaranne Lv 1 64 pts. 9,726
  7. Avatar for SKSbell 117. SKSbell Lv 1 64 pts. 9,723
  8. Avatar for RLDallas55 118. RLDallas55 Lv 1 64 pts. 9,721
  9. Avatar for dilli 119. dilli Lv 1 63 pts. 9,717
  10. Avatar for BuzzDee 120. BuzzDee Lv 1 63 pts. 9,714

Comments

beta_helix Staff Lv 1

This is the Quest to the Native version of Puzzle 390:
http://fold.it/portal/node/989012

Now that the protein has been solved (thanks to all of you), the PDB has posted the solution:
http://pdb.rcsb.org/pdb/explore.do?structureId=3SQF

For hints on how to use Partial Threading with the Alignment Tool, check out: http://fold.it/portal/node/989012#comment-9780

And if you weren't playing Foldit last December and want to see if you would have been able to get close to the native, you can always turn off the guide by press Shift-S.