Placeholder image of a protein
Icon representing a puzzle

460: Quest to the SOLVED Monkey Virus Protein

Closed since over 14 years ago

Intermediate Overall Prediction

Summary

Created
September 23, 2011
Expires
Max points
100
Description

The crystal structure of monomeric M-PMV retroviral protease, which causes AIDS in rhesus monkeys, has finally been released. You may have read about this protein in the news recently... so we thought we should post it again as a Quest to the Native. Once again we are giving you the 10 NMR models to work on, they are also in the Alignment Tool. After threading, make sure to press G to Align the Guide. We're sure you can get even closer to the native this time, and in less than 10 days!

Top groups

  1. Avatar for Deleted group 21. Deleted group pts. 9,710
  2. Avatar for Penny-Arcade 22. Penny-Arcade 6 pts. 9,672
  3. Avatar for Freedom Folders 23. Freedom Folders 5 pts. 9,670
  4. Avatar for Eὕρηκα! Heureka! 24. Eὕρηκα! Heureka! 4 pts. 9,585
  5. Avatar for Peperoni Pizza 25. Peperoni Pizza 4 pts. 9,539
  6. Avatar for Deleted group 26. Deleted group pts. 9,435
  7. Avatar for Team Canada 27. Team Canada 3 pts. 9,429
  8. Avatar for ROMANIA Team 28. ROMANIA Team 2 pts. 9,345
  9. Avatar for name_in_progress 29. name_in_progress 2 pts. 9,298
  10. Avatar for HMT heritage 30. HMT heritage 1 pt. 9,277
  1. Avatar for victhebrick1 981. victhebrick1 Lv 1 1 pt. 7,811
  2. Avatar for Medizinstudent 982. Medizinstudent Lv 1 1 pt. 7,804
  3. Avatar for georged 983. georged Lv 1 1 pt. 7,802
  4. Avatar for calphalon 984. calphalon Lv 1 1 pt. 7,800
  5. Avatar for warb 985. warb Lv 1 1 pt. 7,800
  6. Avatar for MarcoRai 986. MarcoRai Lv 1 1 pt. 7,800
  7. Avatar for MattRussNC 987. MattRussNC Lv 1 1 pt. 7,799
  8. Avatar for Blackboxeq 988. Blackboxeq Lv 1 1 pt. 7,792
  9. Avatar for audredge 989. audredge Lv 1 1 pt. 7,779
  10. Avatar for justinphilpott 990. justinphilpott Lv 1 1 pt. 7,779

Comments

beta_helix Staff Lv 1

This is the Quest to the Native version of Puzzle 390:
http://fold.it/portal/node/989012

Now that the protein has been solved (thanks to all of you), the PDB has posted the solution:
http://pdb.rcsb.org/pdb/explore.do?structureId=3SQF

For hints on how to use Partial Threading with the Alignment Tool, check out: http://fold.it/portal/node/989012#comment-9780

And if you weren't playing Foldit last December and want to see if you would have been able to get close to the native, you can always turn off the guide by press Shift-S.