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460: Quest to the SOLVED Monkey Virus Protein

Closed since over 14 years ago

Intermediate Overall Prediction

Summary

Created
September 23, 2011
Expires
Max points
100
Description

The crystal structure of monomeric M-PMV retroviral protease, which causes AIDS in rhesus monkeys, has finally been released. You may have read about this protein in the news recently... so we thought we should post it again as a Quest to the Native. Once again we are giving you the 10 NMR models to work on, they are also in the Alignment Tool. After threading, make sure to press G to Align the Guide. We're sure you can get even closer to the native this time, and in less than 10 days!

Top groups

  1. Avatar for Hungary 31. Hungary 1 pt. 9,276
  2. Avatar for BOINC@Poland 32. BOINC@Poland 1 pt. 9,243
  3. Avatar for Deleted group 33. Deleted group pts. 9,183
  4. Avatar for ProTeam 34. ProTeam 1 pt. 9,151
  5. Avatar for Ukraine 35. Ukraine 1 pt. 9,149
  6. Avatar for Crunching Family 36. Crunching Family 1 pt. 9,126
  7. Avatar for Deleted group 37. Deleted group pts. 9,098
  8. Avatar for Team Toombs 38. Team Toombs 1 pt. 9,050
  9. Avatar for DSN @ Home 39. DSN @ Home 1 pt. 9,045
  10. Avatar for Team China 40. Team China 1 pt. 9,034
  1. Avatar for dylanmance 891. dylanmance Lv 1 1 pt. 8,324
  2. Avatar for lkk77 892. lkk77 Lv 1 1 pt. 8,323
  3. Avatar for fabry974 893. fabry974 Lv 1 1 pt. 8,307
  4. Avatar for untitledH 894. untitledH Lv 1 1 pt. 8,302
  5. Avatar for toolsoldier 895. toolsoldier Lv 1 1 pt. 8,298
  6. Avatar for Naseweis 896. Naseweis Lv 1 1 pt. 8,297
  7. Avatar for TGDirector 897. TGDirector Lv 1 1 pt. 8,297
  8. Avatar for Psydefx 898. Psydefx Lv 1 1 pt. 8,274
  9. Avatar for Kyber 899. Kyber Lv 1 1 pt. 8,268
  10. Avatar for bhawkes 900. bhawkes Lv 1 1 pt. 8,257

Comments

beta_helix Staff Lv 1

This is the Quest to the Native version of Puzzle 390:
http://fold.it/portal/node/989012

Now that the protein has been solved (thanks to all of you), the PDB has posted the solution:
http://pdb.rcsb.org/pdb/explore.do?structureId=3SQF

For hints on how to use Partial Threading with the Alignment Tool, check out: http://fold.it/portal/node/989012#comment-9780

And if you weren't playing Foldit last December and want to see if you would have been able to get close to the native, you can always turn off the guide by press Shift-S.