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460: Quest to the SOLVED Monkey Virus Protein

Closed since over 14 years ago

Intermediate Overall Prediction

Summary


Created
September 23, 2011
Expires
Max points
100
Description

The crystal structure of monomeric M-PMV retroviral protease, which causes AIDS in rhesus monkeys, has finally been released. You may have read about this protein in the news recently... so we thought we should post it again as a Quest to the Native. Once again we are giving you the 10 NMR models to work on, they are also in the Alignment Tool. After threading, make sure to press G to Align the Guide. We're sure you can get even closer to the native this time, and in less than 10 days!

Top groups


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  3. Avatar for foldeRNA 3. foldeRNA 81 pts. 10,470
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  5. Avatar for Androids 5. Androids 65 pts. 10,465
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  2. Avatar for scabby5 1112. scabby5 Lv 1 1 pt. 6,271
  3. Avatar for poof312 1113. poof312 Lv 1 1 pt. 6,259
  4. Avatar for dbartles824 1114. dbartles824 Lv 1 1 pt. 6,166
  5. Avatar for ThePowerIHold 1115. ThePowerIHold Lv 1 1 pt. 6,149
  6. Avatar for moli 1116. moli Lv 1 1 pt. 6,142
  7. Avatar for tdugger 1117. tdugger Lv 1 1 pt. 5,552
  8. Avatar for 0xF15H13 1118. 0xF15H13 Lv 1 1 pt. 4,886
  9. Avatar for bkandimalla 1119. bkandimalla Lv 1 1 pt. 4,857
  10. Avatar for nadians 1120. nadians Lv 1 1 pt. 4,682

Comments


beta_helix Staff Lv 1

This is the Quest to the Native version of Puzzle 390:
http://fold.it/portal/node/989012

Now that the protein has been solved (thanks to all of you), the PDB has posted the solution:
http://pdb.rcsb.org/pdb/explore.do?structureId=3SQF

For hints on how to use Partial Threading with the Alignment Tool, check out: http://fold.it/portal/node/989012#comment-9780

And if you weren't playing Foldit last December and want to see if you would have been able to get close to the native, you can always turn off the guide by press Shift-S.