Placeholder image of a protein
Icon representing a puzzle

460: Quest to the SOLVED Monkey Virus Protein

Closed since over 14 years ago

Intermediate Overall Prediction

Summary

Created
September 23, 2011
Expires
Max points
100
Description

The crystal structure of monomeric M-PMV retroviral protease, which causes AIDS in rhesus monkeys, has finally been released. You may have read about this protein in the news recently... so we thought we should post it again as a Quest to the Native. Once again we are giving you the 10 NMR models to work on, they are also in the Alignment Tool. After threading, make sure to press G to Align the Guide. We're sure you can get even closer to the native this time, and in less than 10 days!

Top groups

  1. Avatar for Void Crushers
    1. Void Crushers
    100 pts. 10,577
  2. Avatar for Anthropic Dreams 2. Anthropic Dreams 91 pts. 10,474
  3. Avatar for foldeRNA 3. foldeRNA 81 pts. 10,470
  4. Avatar for Contenders 4. Contenders 73 pts. 10,467
  5. Avatar for Androids 5. Androids 65 pts. 10,465
  6. Avatar for Go Science 6. Go Science 58 pts. 10,445
  7. Avatar for Russian team 7. Russian team 52 pts. 10,381
  8. Avatar for Natural Abilities 8. Natural Abilities 46 pts. 10,339
  9. Avatar for Deleted group 9. Deleted group pts. 10,171
  10. Avatar for SQUID 10. SQUID 36 pts. 10,156
  1. Avatar for sgriffin 1181. sgriffin Lv 1 1 pt. 0
  2. Avatar for vlada111 1182. vlada111 Lv 1 1 pt. 0
  3. Avatar for alles777 1183. alles777 Lv 1 1 pt. 0
  4. Avatar for UniverseMike 1184. UniverseMike Lv 1 1 pt. 0
  5. Avatar for mandieedee 1185. mandieedee Lv 1 1 pt. 0
  6. Avatar for atpandme 1186. atpandme Lv 1 1 pt. 0
  7. Avatar for Marcello1977pa 1187. Marcello1977pa Lv 1 1 pt. 0
  8. Avatar for mhdidone 1188. mhdidone Lv 1 1 pt. 0
  9. Avatar for BenGIEF 1189. BenGIEF Lv 1 1 pt. 0
  10. Avatar for lockdale 1190. lockdale Lv 1 1 pt. 0

Comments

beta_helix Staff Lv 1

This is the Quest to the Native version of Puzzle 390:
http://fold.it/portal/node/989012

Now that the protein has been solved (thanks to all of you), the PDB has posted the solution:
http://pdb.rcsb.org/pdb/explore.do?structureId=3SQF

For hints on how to use Partial Threading with the Alignment Tool, check out: http://fold.it/portal/node/989012#comment-9780

And if you weren't playing Foldit last December and want to see if you would have been able to get close to the native, you can always turn off the guide by press Shift-S.