Placeholder image of a protein
Icon representing a puzzle

460: Quest to the SOLVED Monkey Virus Protein

Closed since over 14 years ago

Intermediate Overall Prediction

Summary


Created
September 23, 2011
Expires
Max points
100
Description

The crystal structure of monomeric M-PMV retroviral protease, which causes AIDS in rhesus monkeys, has finally been released. You may have read about this protein in the news recently... so we thought we should post it again as a Quest to the Native. Once again we are giving you the 10 NMR models to work on, they are also in the Alignment Tool. After threading, make sure to press G to Align the Guide. We're sure you can get even closer to the native this time, and in less than 10 days!

Top groups


  1. Avatar for Void Crushers 100 pts. 10,577
  2. Avatar for Anthropic Dreams 2. Anthropic Dreams 91 pts. 10,474
  3. Avatar for foldeRNA 3. foldeRNA 81 pts. 10,470
  4. Avatar for Contenders 4. Contenders 73 pts. 10,467
  5. Avatar for Androids 5. Androids 65 pts. 10,465
  6. Avatar for Go Science 6. Go Science 58 pts. 10,445
  7. Avatar for Russian team 7. Russian team 52 pts. 10,381
  8. Avatar for Natural Abilities 8. Natural Abilities 46 pts. 10,339
  9. Avatar for Deleted group 9. Deleted group pts. 10,171
  10. Avatar for SQUID 10. SQUID 36 pts. 10,156

  1. Avatar for Noah Bazarov 791. Noah Bazarov Lv 1 2 pts. 8,612
  2. Avatar for flynng 792. flynng Lv 1 2 pts. 8,611
  3. Avatar for luca1990 793. luca1990 Lv 1 2 pts. 8,610
  4. Avatar for zachsch 794. zachsch Lv 1 2 pts. 8,607
  5. Avatar for dragoon11024 795. dragoon11024 Lv 1 2 pts. 8,607
  6. Avatar for mrzack 796. mrzack Lv 1 2 pts. 8,604
  7. Avatar for Anonymous1234 797. Anonymous1234 Lv 1 2 pts. 8,603
  8. Avatar for mberna00 798. mberna00 Lv 1 2 pts. 8,601
  9. Avatar for ykara 799. ykara Lv 1 2 pts. 8,601
  10. Avatar for florencioh 800. florencioh Lv 1 2 pts. 8,601

Comments


beta_helix Staff Lv 1

This is the Quest to the Native version of Puzzle 390:
http://fold.it/portal/node/989012

Now that the protein has been solved (thanks to all of you), the PDB has posted the solution:
http://pdb.rcsb.org/pdb/explore.do?structureId=3SQF

For hints on how to use Partial Threading with the Alignment Tool, check out: http://fold.it/portal/node/989012#comment-9780

And if you weren't playing Foldit last December and want to see if you would have been able to get close to the native, you can always turn off the guide by press Shift-S.