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460 (<15): Quest to the SOLVED Monkey Virus Protein

Closed since over 14 years ago

Intermediate

Summary


Created
September 23, 2011
Expires
Max points
100
Description

The crystal structure of monomeric M-PMV retroviral protease, which causes AIDS in rhesus monkeys, has finally been released. You may have read about this protein in the news recently... so we thought we should post it again as a Quest to the Native. Once again we are giving you the 10 NMR models to work on, they are also in the Alignment Tool. After threading, make sure to press G to Align the Guide. We're sure you can get even closer to the native this time, and in less than 10 days! For players with fewer than 15 global points.

Top groups


  1. Avatar for name_in_progress 11. name_in_progress 11 pts. 9,550
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  5. Avatar for Void Crushers 16. Void Crushers 3 pts. 9,358
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  7. Avatar for BOINC@Poland 18. BOINC@Poland 1 pt. 9,220
  8. Avatar for Ukraine 19. Ukraine 1 pt. 9,147
  9. Avatar for Minions of TWIS 20. Minions of TWIS 1 pt. 9,141

  1. Avatar for JIM1988 231. JIM1988 Lv 1 14 pts. 9,066
  2. Avatar for irfankaya 232. irfankaya Lv 1 14 pts. 9,066
  3. Avatar for Raush 233. Raush Lv 1 14 pts. 9,065
  4. Avatar for Susume 234. Susume Lv 1 14 pts. 9,065
  5. Avatar for spidermo 235. spidermo Lv 1 14 pts. 9,064
  6. Avatar for TheAncient 236. TheAncient Lv 1 14 pts. 9,063
  7. Avatar for ewsnyder 237. ewsnyder Lv 1 14 pts. 9,057
  8. Avatar for osebastian 238. osebastian Lv 1 13 pts. 9,056
  9. Avatar for Reinderien 239. Reinderien Lv 1 13 pts. 9,055
  10. Avatar for Andreitalee 240. Andreitalee Lv 1 13 pts. 9,055

Comments


beta_helix Staff Lv 1

CLICK HERE:
http://fold.it/portal/node/988864


This was the famous Unsolved Monkey Virus Protein

This is the Quest to the Native version of Puzzle 390:
http://fold.it/portal/node/989012

Now that the protein has been solved (thanks to all of you), the PDB has posted the solution:
http://pdb.rcsb.org/pdb/explore.do?structureId=3SQF

For hints on how to use Partial Threading with the Alignment Tool, check out: http://fold.it/portal/node/989012#comment-9780

And if you weren't playing Foldit last December and want to see if you would have been able to get close to the native, you can always turn off the guide by press Shift-S.