Placeholder image of a protein
Icon representing a puzzle

460 (<15): Quest to the SOLVED Monkey Virus Protein

Closed since over 14 years ago

Intermediate

Summary

Created
September 23, 2011
Expires
Max points
100
Description

The crystal structure of monomeric M-PMV retroviral protease, which causes AIDS in rhesus monkeys, has finally been released. You may have read about this protein in the news recently... so we thought we should post it again as a Quest to the Native. Once again we are giving you the 10 NMR models to work on, they are also in the Alignment Tool. After threading, make sure to press G to Align the Guide. We're sure you can get even closer to the native this time, and in less than 10 days! For players with fewer than 15 global points.

Top groups

  1. Avatar for name_in_progress 11. name_in_progress 11 pts. 9,550
  2. Avatar for Rule Britannia 12. Rule Britannia 9 pts. 9,550
  3. Avatar for SQUID 13. SQUID 7 pts. 9,523
  4. Avatar for Planet IX 14. Planet IX 5 pts. 9,479
  5. Avatar for Richard Dawkins Foundation 15. Richard Dawkins Foundation 4 pts. 9,384
  6. Avatar for Void Crushers 16. Void Crushers 3 pts. 9,358
  7. Avatar for HMT heritage 17. HMT heritage 2 pts. 9,322
  8. Avatar for BOINC@Poland 18. BOINC@Poland 1 pt. 9,220
  9. Avatar for Ukraine 19. Ukraine 1 pt. 9,147
  10. Avatar for Minions of TWIS 20. Minions of TWIS 1 pt. 9,141
  1. Avatar for Pyrron 451. Pyrron Lv 1 1 pt. 8,604
  2. Avatar for jcw608 452. jcw608 Lv 1 1 pt. 8,603
  3. Avatar for JonanNieto 453. JonanNieto Lv 1 1 pt. 8,602
  4. Avatar for tiagoversuti 454. tiagoversuti Lv 1 1 pt. 8,602
  5. Avatar for dkmfan 455. dkmfan Lv 1 1 pt. 8,597
  6. Avatar for KOR KIM 456. KOR KIM Lv 1 1 pt. 8,594
  7. Avatar for Jheat 457. Jheat Lv 1 1 pt. 8,591
  8. Avatar for nhagler 458. nhagler Lv 1 1 pt. 8,579
  9. Avatar for carbonhyperbole 459. carbonhyperbole Lv 1 1 pt. 8,576
  10. Avatar for sub8rosa 460. sub8rosa Lv 1 1 pt. 8,576

Comments

beta_helix Staff Lv 1

CLICK HERE:
http://fold.it/portal/node/988864

This was the famous Unsolved Monkey Virus Protein

This is the Quest to the Native version of Puzzle 390:
http://fold.it/portal/node/989012

Now that the protein has been solved (thanks to all of you), the PDB has posted the solution:
http://pdb.rcsb.org/pdb/explore.do?structureId=3SQF

For hints on how to use Partial Threading with the Alignment Tool, check out: http://fold.it/portal/node/989012#comment-9780

And if you weren't playing Foldit last December and want to see if you would have been able to get close to the native, you can always turn off the guide by press Shift-S.