Placeholder image of a protein
Icon representing a puzzle

460 (<15): Quest to the SOLVED Monkey Virus Protein

Closed since over 14 years ago

Intermediate

Summary

Created
September 23, 2011
Expires
Max points
100
Description

The crystal structure of monomeric M-PMV retroviral protease, which causes AIDS in rhesus monkeys, has finally been released. You may have read about this protein in the news recently... so we thought we should post it again as a Quest to the Native. Once again we are giving you the 10 NMR models to work on, they are also in the Alignment Tool. After threading, make sure to press G to Align the Guide. We're sure you can get even closer to the native this time, and in less than 10 days! For players with fewer than 15 global points.

Top groups

  1. Avatar for name_in_progress 11. name_in_progress 11 pts. 9,550
  2. Avatar for Rule Britannia 12. Rule Britannia 9 pts. 9,550
  3. Avatar for SQUID 13. SQUID 7 pts. 9,523
  4. Avatar for Planet IX 14. Planet IX 5 pts. 9,479
  5. Avatar for Richard Dawkins Foundation 15. Richard Dawkins Foundation 4 pts. 9,384
  6. Avatar for Void Crushers 16. Void Crushers 3 pts. 9,358
  7. Avatar for HMT heritage 17. HMT heritage 2 pts. 9,322
  8. Avatar for BOINC@Poland 18. BOINC@Poland 1 pt. 9,220
  9. Avatar for Ukraine 19. Ukraine 1 pt. 9,147
  10. Avatar for Minions of TWIS 20. Minions of TWIS 1 pt. 9,141
  1. Avatar for PierValerio 571. PierValerio Lv 1 1 pt. 7,667
  2. Avatar for blackelectricity 572. blackelectricity Lv 1 1 pt. 7,656
  3. Avatar for koltoroc 573. koltoroc Lv 1 1 pt. 7,653
  4. Avatar for GhostlyIan 574. GhostlyIan Lv 1 1 pt. 7,652
  5. Avatar for j0r 575. j0r Lv 1 1 pt. 7,649
  6. Avatar for keght 576. keght Lv 1 1 pt. 7,619
  7. Avatar for mabee 577. mabee Lv 1 1 pt. 7,619
  8. Avatar for bernhejd 578. bernhejd Lv 1 1 pt. 7,614
  9. Avatar for elikagan 579. elikagan Lv 1 1 pt. 7,585
  10. Avatar for Erik92 580. Erik92 Lv 1 1 pt. 7,573

Comments

beta_helix Staff Lv 1

CLICK HERE:
http://fold.it/portal/node/988864

This was the famous Unsolved Monkey Virus Protein

This is the Quest to the Native version of Puzzle 390:
http://fold.it/portal/node/989012

Now that the protein has been solved (thanks to all of you), the PDB has posted the solution:
http://pdb.rcsb.org/pdb/explore.do?structureId=3SQF

For hints on how to use Partial Threading with the Alignment Tool, check out: http://fold.it/portal/node/989012#comment-9780

And if you weren't playing Foldit last December and want to see if you would have been able to get close to the native, you can always turn off the guide by press Shift-S.