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485: Quick Alignment Puzzle 482

Closed since over 14 years ago

Intermediate Intermediate Overall Overall Prediction Prediction

Summary

Created
November 27, 2011
Expires
Max points
100
Description

This is a quick repost of Puzzle 482: Advanced Alignment Puzzle, but this time we are providing you with secondary structure predictions that are posted in the puzzle comments and included in the starting structure as well. These predictions are from the SAM-T08 server (as requested in the previous puzzle comments: http://fold.it/portal/node/991105). Check out that page for more hints and make sure you beat Intro Puzzles 6-1 through 6-3 before playing this puzzle.

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Comments

beta_helix Staff Lv 1

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the two Valines at residues 84 & 86 are highly predicted to be part of a sheet. However, the Valine at residue 9 is predicted to be either part of a loop or sheet.