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487: CASP ROLL Puzzle 1

Closed since over 14 years ago

Advanced Overall Prediction

Summary

Created
December 01, 2011
Expires
Max points
100
Description

This is the first CASP ROLL target: R0001. We are giving it to you as a freestyle puzzle while we wait for the server predictions to come back. We are providing you with secondary structure predictions that are posted in the puzzle comments and included in the starting structure as well. It's 183 residues long, but get used to this protein because it's deadlline isn't until February!

Top groups

  1. Avatar for Nerdfighters 31. Nerdfighters 1 pt. 9,390
  2. Avatar for Czech National Team 32. Czech National Team 1 pt. 9,366
  3. Avatar for Bree Fradley Manning 33. Bree Fradley Manning 1 pt. 9,216
  4. Avatar for Deleted group 34. Deleted group pts. 9,006
  5. Avatar for TSC! Russia 35. TSC! Russia 1 pt. 8,765
  6. Avatar for Penny-Arcade 36. Penny-Arcade 1 pt. 8,491
  7. Avatar for Team Germany 1 37. Team Germany 1 1 pt. 8,076
  8. Avatar for CHNO Junkies 38. CHNO Junkies 1 pt. 7,250
  9. Avatar for DSN @ Home 39. DSN @ Home 1 pt. 7,189
  10. Avatar for Deleted group 40. Deleted group pts. 4,358
  1. Avatar for LiluBio 401. LiluBio Lv 1 1 pt. 7,247
  2. Avatar for McPeate 402. McPeate Lv 1 1 pt. 7,247
  3. Avatar for matsieee 403. matsieee Lv 1 1 pt. 7,247
  4. Avatar for alienalias 404. alienalias Lv 1 1 pt. 7,245
  5. Avatar for Foogleplex 405. Foogleplex Lv 1 1 pt. 7,245
  6. Avatar for Tesla UA 406. Tesla UA Lv 1 1 pt. 7,242
  7. Avatar for tpiccinini 407. tpiccinini Lv 1 1 pt. 7,241
  8. Avatar for derekschwantner 408. derekschwantner Lv 1 1 pt. 7,241
  9. Avatar for izumi80 409. izumi80 Lv 1 1 pt. 7,241
  10. Avatar for tkoolen 410. tkoolen Lv 1 1 pt. 7,241

Comments

beta_helix Staff Lv 1

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valine at residue 3 is highly predicted to be part of a sheet. However, the Valine at residue 116 is predicted to be anything.

Parclytaxel Lv 1

It seems like the placement and identity of the other segments force that sequence to be a loop, rather than a (as predicted by the server to be slightly more likely) sheet.

B_2 Lv 1

Is this a previously unsolved protein, or is this just enhancing a known or previously predicted structure?

I can't tell from the CASP site, since 90% of what's on there is gibberish to a layman.