Placeholder image of a protein
Icon representing a puzzle

487: CASP ROLL Puzzle 1

Closed since over 14 years ago

Advanced Overall Prediction

Summary

Created
December 01, 2011
Expires
Max points
100
Description

This is the first CASP ROLL target: R0001. We are giving it to you as a freestyle puzzle while we wait for the server predictions to come back. We are providing you with secondary structure predictions that are posted in the puzzle comments and included in the starting structure as well. It's 183 residues long, but get used to this protein because it's deadlline isn't until February!

Top groups

  1. Avatar for Contenders
    1. Contenders
    100 pts. 12,215
  2. Avatar for Go Science 2. Go Science 88 pts. 12,051
  3. Avatar for Void Crushers 3. Void Crushers 77 pts. 11,985
  4. Avatar for Anthropic Dreams 4. Anthropic Dreams 68 pts. 11,943
  5. Avatar for Androids 5. Androids 59 pts. 11,908
  6. Avatar for L'Alliance Francophone 6. L'Alliance Francophone 51 pts. 11,906
  7. Avatar for foldeRNA 7. foldeRNA 44 pts. 11,606
  8. Avatar for Russian team 8. Russian team 38 pts. 11,562
  9. Avatar for Deleted group 9. Deleted group pts. 11,527
  10. Avatar for BOINC@Poland 10. BOINC@Poland 27 pts. 11,506
  1. Avatar for spmm 91. spmm Lv 1 39 pts. 11,034
  2. Avatar for goastano 92. goastano Lv 1 39 pts. 11,031
  3. Avatar for B_2 93. B_2 Lv 1 38 pts. 11,031
  4. Avatar for kevin everington 94. kevin everington Lv 1 38 pts. 11,031
  5. Avatar for manu8170 95. manu8170 Lv 1 37 pts. 11,005
  6. Avatar for j_johnso 96. j_johnso Lv 1 37 pts. 10,993
  7. Avatar for Close At Hand 97. Close At Hand Lv 1 37 pts. 10,991
  8. Avatar for miss wanr 98. miss wanr Lv 1 36 pts. 10,985
  9. Avatar for Celegon 99. Celegon Lv 1 36 pts. 10,979
  10. Avatar for kabubi 100. kabubi Lv 1 35 pts. 10,964

Comments

beta_helix Staff Lv 1

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valine at residue 3 is highly predicted to be part of a sheet. However, the Valine at residue 116 is predicted to be anything.

Parclytaxel Lv 1

It seems like the placement and identity of the other segments force that sequence to be a loop, rather than a (as predicted by the server to be slightly more likely) sheet.

B_2 Lv 1

Is this a previously unsolved protein, or is this just enhancing a known or previously predicted structure?

I can't tell from the CASP site, since 90% of what's on there is gibberish to a layman.