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Beginner Puzzle: Anthrax Lethal Factor Protein

Closed since about 14 years ago

Beginner

Summary

Created
February 11, 2012
Expires
Max points
100
Description

This puzzle is designed for veteran Foldit players to help new players, so this version of the puzzle is only worth 50 global points.

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Comments

beta_helix Staff Lv 1

For those of you interested in knowing the score of the guide, it is at 9213.678. It has not been relaxed or fused at all, so you should be able to improve on that score if you reach the native state. (For example, fusing the native 3 times gives a score of 9415.568)
_______________________

If you are new to Foldit, here are detailed instructions to get you started:
http://fold.it/portal/node/988864

HINT: If you are having trouble with this puzzle, try using the "Align Guide" tool:

By right clicking on a region of the protein (not the guide) it will pull up a menu with 6 tools. The bottom right one is "Align Guide". Clicking on it will align the native guide to the region of the protein you selected.
This will help you see what sections on your protein correspond to the guide!

Working with the guide is much more user friendly when you use the advanced viewing options.
In the game click on Menu->General Options and select "Show Advanced GUI" and click Done.
Click on View, turn on 'Show Outline,' set the background color to white, and view stubs on the sidechains, view the guide, and set color relative to guide. Turn all the other view options off."

For even more info: http://foldit.wikia.com/wiki/Tlaloc%27s_Strategy#Technique_for_Matching_a_Guide