Placeholder image of a protein
Icon representing a puzzle

Beginner Puzzle (<150): Anthrax Lethal Factor Protein

Closed since about 14 years ago

Beginner

Summary

Created
February 11, 2012
Expires
Max points
100
Description

This is a Beginner puzzle for new players that have recently completed the Intro Puzzles. The starting model is far from the correct native structure, can you use the Foldit tools you just learned to fix the model and match the guide? For help with Intro Puzzles, visit http://tinyurl.com/foldit-help . Make sure you have completed the Intro Puzzles (at least up to Level 4-5) before attempting these more difficult Science Puzzles. For players with fewer than 150 global points.

Top groups

  1. Avatar for xkcd 11. xkcd 23 pts. 9,695
  2. Avatar for Piratenpartei Deutschland 12. Piratenpartei Deutschland 20 pts. 9,631
  3. Avatar for TT-group 13. TT-group 16 pts. 9,574
  4. Avatar for Biology-2nd 14. Biology-2nd 14 pts. 9,548
  5. Avatar for FoldIt@Netherlands 15. FoldIt@Netherlands 11 pts. 9,543
  6. Avatar for Skeptics Guide to the Universe 16. Skeptics Guide to the Universe 9 pts. 9,518
  7. Avatar for Deleted group 17. Deleted group pts. 9,507
  8. Avatar for Crunching Family 18. Crunching Family 6 pts. 9,398
  9. Avatar for Richard Dawkins Foundation 19. Richard Dawkins Foundation 5 pts. 9,368
  10. Avatar for Androids 20. Androids 4 pts. 9,366
  1. Avatar for JackWeaver
    1. JackWeaver Lv 1
    100 pts. 10,076
  2. Avatar for Mike Tate 2. Mike Tate Lv 1 100 pts. 10,014
  3. Avatar for Lecc 3. Lecc Lv 1 99 pts. 9,923
  4. Avatar for ivanlauro 4. ivanlauro Lv 1 99 pts. 9,896
  5. Avatar for 4sakindevil 5. 4sakindevil Lv 1 98 pts. 9,885
  6. Avatar for Sarian 6. Sarian Lv 1 98 pts. 9,857
  7. Avatar for salish99 7. salish99 Lv 1 97 pts. 9,851
  8. Avatar for Liverion France 8. Liverion France Lv 1 97 pts. 9,834
  9. Avatar for AlexSun 9. AlexSun Lv 1 96 pts. 9,816
  10. Avatar for Deleted player 10. Deleted player pts. 9,806

Comments

beta_helix Staff Lv 1

If you are new to Foldit, here are detailed instructions to get you started:
http://fold.it/portal/node/988864

HINT: If you are having trouble with this puzzle, try using the "Align Guide" tool:

By right clicking on a region of the protein (not the guide) it will pull up a menu with 6 tools. The bottom right one is "Align Guide". Clicking on it will align the native guide to the region of the protein you selected.
This will help you see what sections on your protein correspond to the guide!

Working with the guide is much more user friendly when you use the advanced viewing options.
In the game click on Menu->General Options and select "Show Advanced GUI" and click Done.
Click on View, turn on 'Show Outline,' set the background color to white, and view stubs on the sidechains, view the guide, and set color relative to guide. Turn all the other view options off."

For even more info: http://foldit.wikia.com/wiki/Tlaloc%27s_Strategy#Technique_for_Matching_a_Guide