Foldit Player Mark-'s solution for Puzzle 539
Closed since almost 14 years ago
IntermediateSummary
- Created
- April 26, 2012
- Expires
- Max points
- 100
Blogpost about this: http://fold.it/portal/node/992498 . A pretty creative solution where the Trp resides in the cavity and the Leu and Ile make nice hydrophobic contacts (and two backbone hydrogen bonds) with the three prolines in the loop of CTLA-4. This is especially relevant since these prolines make up a part of the native binding site.
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