552: CASP10 Target T0644

Closed since almost 14 years ago

Summary

• Created: May 01, 2012
• Expires: May 11, 2012 at 18:00 UTC
• Max points: 100

Description

Here is the first CASP10 target. This target is 166 residues and we are giving you the top-predicted template from 3 different alignment programs (you'll notice that all 3 programs picked the same template, but slightly different alignments). More details about this CASP target are in the puzzle comments.

Top groups

• 31. Brave New World 1 pt. 7,164
• 32. WSUstudents 1 pt. 0
• 33. DSN @ Home 1 pt. 0

Top soloists

• 151. goastano 6 pts. 10,455
• 152. Close At Hand 6 pts. 10,426
• 153. aendgraend 6 pts. 10,424
• 154. Deleted player pts. 10,388
• 155. Bartosz Grotthus 6 pts. 10,376
• 156. Cyberkashi 6 pts. 10,371
• 157. Acida-2 6 pts. 10,357
• 158. boondog 5 pts. 10,352
• 159. mitarcher 5 pts. 10,351
• 160. Squirrely 5 pts. 10,333

Comments

[beta_helix]

Here is the CASP link for this target (which has the amino acid sequence):
http://predictioncenter.org/casp10/target.cgi?id=40&view=all

[beta_helix]

Here are some other secondary structure predictions (that are sadly not as easy to look at):

H = helix
E = sheet
C = loop (or coil)

The higher the number at the top of each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Phenylalanines at residue 19 & 21 are highly predicted to be part of a helix (an H with a 9 & 8 above it). However, the Phenylalanine at residue 77 is predicted to be in a sheet (an E with a 9 above it).

[beta_helix]

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 12, 16, 18 & 99 are highly predicted to be part of a helix. However, the Valines at residues 62, 74, 130-131 & 139 are highly predicted to be in sheets.