Placeholder image of a protein
Icon representing a puzzle

552: CASP10 Target T0644

Closed since almost 14 years ago

Advanced Overall Prediction

Summary

Created
May 01, 2012
Expires
Max points
100
Description

Here is the first CASP10 target. This target is 166 residues and we are giving you the top-predicted template from 3 different alignment programs (you'll notice that all 3 programs picked the same template, but slightly different alignments). More details about this CASP target are in the puzzle comments.

Top groups

  1. Avatar for Brave New World 31. Brave New World 1 pt. 7,164
  2. Avatar for WSUstudents 32. WSUstudents 1 pt. 0
  3. Avatar for DSN @ Home 33. DSN @ Home 1 pt. 0
  1. Avatar for mberna00 41. mberna00 Lv 1 55 pts. 11,864
  2. Avatar for TheGUmmer 42. TheGUmmer Lv 1 54 pts. 11,854
  3. Avatar for smilingone 43. smilingone Lv 1 53 pts. 11,842
  4. Avatar for marie_s 44. marie_s Lv 1 52 pts. 11,837
  5. Avatar for jakbinimbol 45. jakbinimbol Lv 1 51 pts. 11,836
  6. Avatar for rsosborne 46. rsosborne Lv 1 51 pts. 11,835
  7. Avatar for yoyo washington 47. yoyo washington Lv 1 50 pts. 11,833
  8. Avatar for dembones 48. dembones Lv 1 49 pts. 11,827
  9. Avatar for drjr 49. drjr Lv 1 48 pts. 11,822
  10. Avatar for Bautho 50. Bautho Lv 1 47 pts. 11,805

Comments

beta_helix Staff Lv 1

Here are some other secondary structure predictions (that are sadly not as easy to look at):

H = helix
E = sheet
C = loop (or coil)

The higher the number at the top of each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Phenylalanines at residue 19 & 21 are highly predicted to be part of a helix (an H with a 9 & 8 above it). However, the Phenylalanine at residue 77 is predicted to be in a sheet (an E with a 9 above it).

beta_helix Staff Lv 1

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 12, 16, 18 & 99 are highly predicted to be part of a helix. However, the Valines at residues 62, 74, 130-131 & 139 are highly predicted to be in sheets.