Placeholder image of a protein
Icon representing a puzzle

Beginner Puzzle (<15): Anthrax Lethal Factor Protein

Closed since almost 14 years ago

Beginner Beginner

Summary

Created
May 04, 2012
Expires
Max points
100
Description

This is a Beginner puzzle for new players that have recently completed the Intro Puzzles. The starting model is far from the correct native structure, can you use the Foldit tools you just learned to fix the model and match the guide? For help with Intro Puzzles, visit http://tinyurl.com/foldit-help . Make sure you have completed the Intro Puzzles (at least up to Level 4-5) before attempting these more difficult Science Puzzles. For players with fewer than 15 global points.

Top groups

  1. Avatar for Go Science
    1. Go Science
    100 pts. 10,055
  2. Avatar for Anthropic Dreams 2. Anthropic Dreams 82 pts. 9,787
  3. Avatar for SETI.Germany 3. SETI.Germany 66 pts. 9,650
  4. Avatar for foldeRNA 4. foldeRNA 53 pts. 9,625
  5. Avatar for Team Commonwealth 5. Team Commonwealth 42 pts. 9,525
  6. Avatar for WSUstudents 6. WSUstudents 33 pts. 9,485
  7. Avatar for 7Monkeys 7. 7Monkeys 26 pts. 9,474
  8. Avatar for Richard Dawkins Foundation 8. Richard Dawkins Foundation 20 pts. 9,452
  9. Avatar for xkcd 9. xkcd 15 pts. 9,443
  10. Avatar for Structuralists 10. Structuralists 11 pts. 9,289
  1. Avatar for whyemmy 381. whyemmy Lv 1 18 pts. 8,998
  2. Avatar for CoolgyFurlough 382. CoolgyFurlough Lv 1 18 pts. 8,998
  3. Avatar for Leon Bollmann 383. Leon Bollmann Lv 1 18 pts. 8,997
  4. Avatar for jackfriary 384. jackfriary Lv 1 18 pts. 8,997
  5. Avatar for RustyJar 385. RustyJar Lv 1 18 pts. 8,996
  6. Avatar for bobtheowl2 386. bobtheowl2 Lv 1 17 pts. 8,995
  7. Avatar for allisondobry 387. allisondobry Lv 1 17 pts. 8,995
  8. Avatar for igor torok 388. igor torok Lv 1 17 pts. 8,994
  9. Avatar for JoachimSt 389. JoachimSt Lv 1 17 pts. 8,994
  10. Avatar for Sam The Chemist 390. Sam The Chemist Lv 1 17 pts. 8,993

Comments

beta_helix Staff Lv 1

If you are new to Foldit, here are detailed instructions to get you started:
http://fold.it/portal/node/988864

HINT: If you are having trouble with this puzzle, try using the "Align Guide" tool:

By right clicking on a region of the protein (not the guide) it will pull up a menu with 6 tools. The bottom right one is "Align Guide". Clicking on it will align the native guide to the region of the protein you selected.
This will help you see what sections on your protein correspond to the guide!

Working with the guide is much more user friendly when you use the advanced viewing options.
In the game click on Menu->General Options and select "Show Advanced GUI" and click Done.
Click on View, turn on 'Show Outline,' set the background color to white, and view stubs on the sidechains, view the guide, and set color relative to guide. Turn all the other view options off."

For even more info: http://foldit.wikia.com/wiki/Tlaloc%27s_Strategy#Technique_for_Matching_a_Guide