Placeholder image of a protein
Icon representing a puzzle

559: CASP10 Target T0673

Closed since almost 14 years ago

Advanced Overall Prediction

Summary

Created
May 17, 2012
Expires
Max points
100
Description

This is another tough one! None of the alignment programs were able to find good templates for this target, and it might be the case that this protein has no homologs. Again we are giving you 6 templates (in hope that one of them is correct) for now, and will provide you with some server predictions once they are released. More details about this CASP target are in the puzzle comments.

Top groups

  1. Avatar for Anthropic Dreams
    1. Anthropic Dreams
    100 pts. 10,110
  2. Avatar for Contenders 2. Contenders 84 pts. 10,086
  3. Avatar for Void Crushers 3. Void Crushers 70 pts. 9,998
  4. Avatar for Go Science 4. Go Science 58 pts. 9,993
  5. Avatar for L'Alliance Francophone 5. L'Alliance Francophone 48 pts. 9,981
  6. Avatar for HMT heritage 6. HMT heritage 39 pts. 9,908
  7. Avatar for foldeRNA 7. foldeRNA 32 pts. 9,870
  8. Avatar for FoldIt@Netherlands 8. FoldIt@Netherlands 26 pts. 9,829
  9. Avatar for Gargleblasters 9. Gargleblasters 20 pts. 9,669
  10. Avatar for Deleted group 10. Deleted group pts. 9,635
  1. Avatar for Bletchley Park 11. Bletchley Park Lv 1 86 pts. 9,978
  2. Avatar for Mark- 12. Mark- Lv 1 84 pts. 9,965
  3. Avatar for auntdeen 13. auntdeen Lv 1 83 pts. 9,960
  4. Avatar for keithv 14. keithv Lv 1 82 pts. 9,958
  5. Avatar for stg123123 15. stg123123 Lv 1 80 pts. 9,957
  6. Avatar for mimi 16. mimi Lv 1 79 pts. 9,950
  7. Avatar for pauldunn 17. pauldunn Lv 1 78 pts. 9,947
  8. Avatar for martinzblavy 18. martinzblavy Lv 1 76 pts. 9,946
  9. Avatar for Timo van der Laan 19. Timo van der Laan Lv 1 75 pts. 9,936
  10. Avatar for Aubade00 20. Aubade00 Lv 1 74 pts. 9,924

Comments

beta_helix Staff Lv 1

Here is the CASP link for this target (showing the amino acid sequence):
http://predictioncenter.org/casp10/target.cgi?id=70
__________________

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 6, 7, & 10 are highly predicted to be in a helix. However, the Valines at residues 59, 60, 64 & 65 are predicted to be in a sheet.
__________________

Link to template PDBs:

http://www.pdb.org/pdb/explore/explore.do?structureId=3s4k
http://www.pdb.org/pdb/explore/explore.do?structureId=1olp
http://www.pdb.org/pdb/explore/explore.do?structureId=2w9q
http://www.pdb.org/pdb/explore/explore.do?structureId=2e12
http://www.pdb.org/pdb/explore/explore.do?structureId=3e1e
http://www.pdb.org/pdb/explore/explore.do?structureId=1q6w

Keep in mind that it's very likely that ONLY ONE of these templates is close to the native (if we're lucky!)