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573b: Advanced CASP10 Refinement Puzzle: TR663

Closed since over 13 years ago

Advanced Overall Prediction

Summary

Created
June 11, 2012
Expires
Max points
100
Description

The CASP organizers have told us that two regions of this starting model are incorrect, so we have modified both these regions into 2 extended chains. You can use the alignment tool to thread the remaining original regions. We will repost this puzzle using the unmodifided starting model, letting you load in your solutions from this puzzle. Secondary structure predictions for this Refinement target are posted in the puzzle comments.

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Comments

beta_helix Staff Lv 1

Here is the CASP link for this Refinement target:
http://predictioncenter.org/casp10/target.cgi?id=103&view=refinement
__________________

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Leucines at residues 32 & 115 are highly predicted to be in a sheet. However, the Leucine at residue 103 is predicted to be in a helix.

brow42 Lv 1

The logo seems to have disappeared but Datacute found it for me (perhapse he used the Google search box?) Here it is:

Also I reran the SAM 08 myself, here's what I got (paste this into AA Copy Paste Compare):

H 4-5 H 13-23 E 29-36 E 41-48 E 53-59 E 65-66 H 70-72 H 75-78 H 82-86 H 89 H 95-105 E 110-116 E 121-129 E 134-140 E 146-151

beta_helix Staff Lv 1

It has been reposted in the original comment above as well.

UPDATE, it keeps vanishing, I'll try to post it here:

marie_s Lv 1

Please put comments in these comments not on the puzzle.

Dont forget, foldit works because it is a game, not a work, not a tool to learn things, not a mean to select students…

So you can give advices, why not, but the spirit of foldit is exploring without previous knowledges.