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578 (<150): Beginner Flu Puzzle 4

Closed since almost 14 years ago

Beginner Beginner

Summary

Created
June 14, 2012
Expires
Max points
100
Description

We are looking for the best locations to place & design FIVE linked residues on the surface of Influenza H3 Hemagglutinin. We have placed 2 helices on either side so that it will be easier to build scaffolds for your designs. Mutate the 5 sidechains while looking for good hydrophobic pockets or residues to make strong hydrogen bonds to. If you are new to Foldit, make sure you have completed Intro Puzzle 5-2, and 7-1 through 7-4 before trying this puzzle. For players with fewer than 150 global points.

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