Placeholder image of a protein
Icon representing a puzzle

582: Beginner CASP10 Refinement Puzzle: TR674

Closed since over 13 years ago

Beginner Overall Prediction

Summary

Created
June 22, 2012
Expires
Max points
100
Description

This is the sixth CASP10 Refinement Target. This model was the best human prediction for target T0674. We've been told that ~84% of this model matches the native, so you just need to find which 16% to refine! More info in the puzzle comments.

Top groups

  1. Avatar for Go Science
    1. Go Science
    100 pts. 11,627
  2. Avatar for L'Alliance Francophone 2. L'Alliance Francophone 85 pts. 11,597
  3. Avatar for Contenders 3. Contenders 71 pts. 11,556
  4. Avatar for Anthropic Dreams 4. Anthropic Dreams 60 pts. 11,552
  5. Avatar for foldeRNA 5. foldeRNA 49 pts. 11,542
  6. Avatar for Team China 6. Team China 41 pts. 11,507
  7. Avatar for HMT heritage 7. HMT heritage 33 pts. 11,465
  8. Avatar for FoldIt@Netherlands 8. FoldIt@Netherlands 27 pts. 11,463
  9. Avatar for Void Crushers 9. Void Crushers 22 pts. 11,401
  10. Avatar for putting the eat in meat 10. putting the eat in meat 17 pts. 11,396
  1. Avatar for Uganalandia 241. Uganalandia Lv 1 1 pt. 10,708
  2. Avatar for Jpilkington 242. Jpilkington Lv 1 1 pt. 10,705
  3. Avatar for Mediosthenes 243. Mediosthenes Lv 1 1 pt. 10,704
  4. Avatar for ferr606 244. ferr606 Lv 1 1 pt. 10,701
  5. Avatar for cherry39 245. cherry39 Lv 1 1 pt. 10,698
  6. Avatar for CoachB 246. CoachB Lv 1 1 pt. 10,698
  7. Avatar for lb494 247. lb494 Lv 1 1 pt. 10,685
  8. Avatar for Zach123 248. Zach123 Lv 1 1 pt. 10,681
  9. Avatar for lufr76 249. lufr76 Lv 1 1 pt. 10,678
  10. Avatar for Lezerith 250. Lezerith Lv 1 1 pt. 10,672

Comments

beta_helix Staff Lv 1

This is the page for this CASP10 refinement target:
http://predictioncenter.org/casp10/target.cgi?id=131&view=refinement

Note that the organizers gave us this hint:

"Starting model GDT_TS=84."

GDT_TS=84 essentially means that 84% of the model superimposes correctly onto the native structure:

Secondary Structure Predictions below:

beta_helix Staff Lv 1

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 10, 12 & 45 are highly predicted to be part of a helix. However, the Valine at residue 93 is predicted to be in a sheet.