Foldit

590: CASP10 Target T0728

Closed since over 13 years ago

Summary

Created: July 03, 2012
Expires: July 13, 2012 at 05:00 UTC
Max points: 100

Description

The twelfth CASP10 target is another tough one, as it's 154 residues. We are providing you with 4 different templates, but all of them have a similar topology (that we hope is the correct one!). We will provide you with server predictions soon. More details about this CASP target are in the puzzle comments.

Top groups

11. FoldIt@Netherlands 8 pts. 10,916
12. Natural Abilities 6 pts. 10,683
13. Richard Dawkins Foundation 4 pts. 10,616
14. SETI.Germany 3 pts. 10,305
15. Mojo Risin' 2 pts. 10,301
16. Atlanta 2 pts. 10,298
17. Androids 1 pt. 10,229
18. Deleted group pts. 9,967
19. 7Monkeys 1 pt. 9,869
20. Eὕρηκα! Heureka! 1 pt. 9,042

141. ZeroLeak7 Lv 1 2 pts. 9,575
142. Brewster Lv 1 2 pts. 9,548
143. GreekCivilization Lv 1 2 pts. 9,523
144. mitarcher Lv 1 1 pt. 9,522
145. Bautho Lv 1 1 pt. 9,515
146. monkry Lv 1 1 pt. 9,503
147. ourtown Lv 1 1 pt. 9,475
148. ComputerMage Lv 1 1 pt. 9,475
149. kastberg Lv 1 1 pt. 9,465
150. lamoille Lv 1 1 pt. 9,452

Comments

beta_helix Staff Lv 1

July 03, 2012

Here is the CASP link for this target (showing the amino acid sequence):
http://predictioncenter.org/casp10/target.cgi?id=148
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Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Leucines at residues 8, & 17 are highly predicted to be in a helix. However, the Leucine at residue 60 is predicted to be in a sheet.
__________________

Link to template PDBs:

http://www.pdb.org/pdb/explore/explore.do?structureId=3d33
http://www.pdb.org/pdb/explore/explore.do?structureId=2eig
http://www.pdb.org/pdb/explore/explore.do?structureId=3jqw
http://www.pdb.org/pdb/explore/explore.do?structureId=2l3b