590: CASP10 Target T0728

Closed since over 13 years ago

Summary

• Created: July 03, 2012
• Expires: July 13, 2012 at 05:00 UTC
• Max points: 100

Description

The twelfth CASP10 target is another tough one, as it's 154 residues. We are providing you with 4 different templates, but all of them have a similar topology (that we hope is the correct one!). We will provide you with server predictions soon. More details about this CASP target are in the puzzle comments.

Top groups

• 11. FoldIt@Netherlands 8 pts. 10,916
• 12. Natural Abilities 6 pts. 10,683
• 13. Richard Dawkins Foundation 4 pts. 10,616
• 14. SETI.Germany 3 pts. 10,305
• 15. Mojo Risin' 2 pts. 10,301
• 16. Atlanta 2 pts. 10,298
• 17. Androids 1 pt. 10,229
• 18. Deleted group pts. 9,967
• 19. 7Monkeys 1 pt. 9,869
• 20. Eὕρηκα! Heureka! 1 pt. 9,042

Top soloists

• 71. Deleted player pts. 10,616
• 72. Deleted player pts. 10,615
• 73. Grom 17 pts. 10,607
• 74. Flagg65a 16 pts. 10,606
• 75. BitSpawn 16 pts. 10,599
• 76. bamh 15 pts. 10,584
• 77. weitzen 15 pts. 10,571
• 78. keithv 14 pts. 10,548
• 79. Tyggy Too 14 pts. 10,534
• 80. pvc78 14 pts. 10,516

Comments

[beta_helix]

Here is the CASP link for this target (showing the amino acid sequence):
http://predictioncenter.org/casp10/target.cgi?id=148
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Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Leucines at residues 8, & 17 are highly predicted to be in a helix. However, the Leucine at residue 60 is predicted to be in a sheet.
__________________

Link to template PDBs:

http://www.pdb.org/pdb/explore/explore.do?structureId=3d33
http://www.pdb.org/pdb/explore/explore.do?structureId=2eig
http://www.pdb.org/pdb/explore/explore.do?structureId=3jqw
http://www.pdb.org/pdb/explore/explore.do?structureId=2l3b