Placeholder image of a protein
Icon representing a puzzle

598: CASP10 Refinement Puzzle: TR712

Closed since over 13 years ago

Intermediate Overall Prediction

Summary

Created
July 10, 2012
Expires
Max points
100
Description

This is the eleventh CASP10 Refinement Target. This model was the best server prediction for target T0712, generated by the MUFOLD-Server. We've been told that ~92% of this model matches the native! So (for once) you won't need to change the starting model much. In addition, the organizers have told us "Regions worth specific attention: 43-52, 79-92, 104-118." These are highlighted in Note Mode.

Top groups

  1. Avatar for SETI.Germany 21. SETI.Germany 1 pt. 12,286
  2. Avatar for Eὕρηκα! Heureka! 22. Eὕρηκα! Heureka! 1 pt. 12,240
  3. Avatar for Minions of TWIS 23. Minions of TWIS 1 pt. 12,024
  4. Avatar for The Enlightened Flamingoes 24. The Enlightened Flamingoes 1 pt. 12,015
  5. Avatar for Skeptics Guide to the Universe 25. Skeptics Guide to the Universe 1 pt. 11,957
  6. Avatar for Geekdo 26. Geekdo 1 pt. 11,393
  7. Avatar for DSN @ Home 27. DSN @ Home 1 pt. 11,055
  1. Avatar for tigger3370 201. tigger3370 Lv 1 1 pt. 11,198
  2. Avatar for yorinagak 202. yorinagak Lv 1 1 pt. 11,111
  3. Avatar for sciencenerd13 203. sciencenerd13 Lv 1 1 pt. 11,091
  4. Avatar for aspadistra 204. aspadistra Lv 1 1 pt. 11,055
  5. Avatar for MalcolmW 205. MalcolmW Lv 1 1 pt. 10,878
  6. Avatar for packer 206. packer Lv 1 1 pt. 10,802
  7. Avatar for Vie 207. Vie Lv 1 1 pt. 10,035
  8. Avatar for RexXxMaster 208. RexXxMaster Lv 1 1 pt. 9,462
  9. Avatar for Inafalutamen 209. Inafalutamen Lv 1 1 pt. 9,280
  10. Avatar for ingoneato 210. ingoneato Lv 1 1 pt. 9,280

Comments

beta_helix Staff Lv 1

This is the page for this CASP10 refinement target:
http://predictioncenter.org/casp10/target.cgi?id=170

Note that the organizers gave us this hint:

"Starting model GDT_TS=92. Regions worth specific attention: 43-52, 79-92, 104-118."

GDT_TS=92 essentially means that 92% of the model superimposes correctly onto the native structure:

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 18, 20, 42 & 148 are highly predicted to be part of a sheet. However, the Valine at residue 105 is predicted to be in anything.