Foldit

600: CASP10 Target T0743

Closed since over 13 years ago

Summary

Created: July 11, 2012
Expires: July 25, 2012 at 14:00 UTC
Max points: 100

Description

Foldit's 600th puzzle is hopefully the last non-refinement CASP10 target! We are providing you with the top templates found by 3 different alignment programs. We will provide you with server predictions soon. More details about this CASP target are in the puzzle comments.

Top groups

11. FoldIt@Netherlands 9 pts. 10,743
12. Natural Abilities 7 pts. 10,718
13. putting the eat in meat 5 pts. 10,554
14. Needles and Pins 4 pts. 10,470
15. Deleted group pts. 10,366
16. SETI.Germany 2 pts. 10,281
17. Mojo Risin' 1 pt. 10,253
18. Russian team 1 pt. 10,221
19. 7Monkeys 1 pt. 10,105
20. Skeptics Guide to the Universe 1 pt. 10,099

81. Deleted player pts. 10,530
82. randomlil Lv 1 12 pts. 10,528
83. heather-1 Lv 1 12 pts. 10,519
84. Kevonni Lv 1 11 pts. 10,478
85. justjustin Lv 1 11 pts. 10,475
86. onursavas Lv 1 11 pts. 10,470
87. anne romaine Lv 1 10 pts. 10,466
88. fishercat Lv 1 10 pts. 10,453
89. boondog Lv 1 10 pts. 10,444
90. alwen Lv 1 9 pts. 10,429

Comments

beta_helix Staff Lv 1

July 11, 2012

Here is the CASP link for this target (showing the amino acid sequence):
http://predictioncenter.org/casp10/target.cgi?id=168
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Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Leucines at residues 22, 28, 78, 91 & 94 are highly predicted to be in a helix. However, the Leucines at residues 109 & 144 are predicted to be in a sheet.
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Link to template PDBs:

http://www.pdb.org/pdb/explore/explore.do?structureId=3fh1
http://www.pdb.org/pdb/explore/explore.do?structureId=2cw9
http://www.pdb.org/pdb/explore/explore.do?structureId=3k7c