Foldit

600: CASP10 Target T0743

Closed since over 13 years ago

Summary

Created: July 11, 2012
Expires: July 25, 2012 at 14:00 UTC
Max points: 100

Description

Foldit's 600th puzzle is hopefully the last non-refinement CASP10 target! We are providing you with the top templates found by 3 different alignment programs. We will provide you with server predictions soon. More details about this CASP target are in the puzzle comments.

Top groups

21. NETD 1 pt. 9,660
22. Deleted group pts. 9,517
23. Czech National Team 1 pt. 8,364
24. Freedom Folders 1 pt. 8,154
25. Geekdo 1 pt. 7,532
26. Minions of TWIS 1 pt. 7,522
27. DSN @ Home 1 pt. 5,833

91. pgiles Lv 1 9 pts. 10,395
92. AsDawnBreaks Lv 1 9 pts. 10,366
93. tscherulli Lv 1 9 pts. 10,350
94. FreeFolder Lv 1 8 pts. 10,345
95. abiogenesis Lv 1 8 pts. 10,338
96. RuneHakubi Lv 1 8 pts. 10,333
97. twisted1 Lv 1 7 pts. 10,310
98. barbaranne Lv 1 7 pts. 10,284
99. Bautho Lv 1 7 pts. 10,281
100. Merf Lv 1 7 pts. 10,270

Comments

beta_helix Staff Lv 1

July 11, 2012

Here is the CASP link for this target (showing the amino acid sequence):
http://predictioncenter.org/casp10/target.cgi?id=168
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Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Leucines at residues 22, 28, 78, 91 & 94 are highly predicted to be in a helix. However, the Leucines at residues 109 & 144 are predicted to be in a sheet.
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Link to template PDBs:

http://www.pdb.org/pdb/explore/explore.do?structureId=3fh1
http://www.pdb.org/pdb/explore/explore.do?structureId=2cw9
http://www.pdb.org/pdb/explore/explore.do?structureId=3k7c